Telmisartan

Hypertension Treatment of essential hypertension in adults. Cardiovascular prevention Reduction of cardiovascular morbidity in adults with: • manifest atherothrombotic cardiovascular disease (history of coronary heart disease, stroke, or peripheral arterial disease) or • type 2 diabetes mellitus with documented target organ damage

Treatment of Essential Hypertension MICARDIS (telmisartan) is indicated for the treatment of mild to moderate essential hypertension in adults. MICARDIS may be used alone or in combination with thiazide diuretics. The concurrent use with angiotensin converting enzyme inhibitors is not recommended.

Risk Reduction of Cardiovascular Morbidity MICARDIS is indicated to reduce the risk of non-fatal stroke or non-fatal myocardial infarction in adults 55 years or older at high risk of developing major cardiovascular events who cannot tolerate an angiotensin converting enzyme inhibitor (ACEI).

High risk of cardiovascular events includes evidence of coronary artery disease, peripheral arterial disease, stroke, transient ischemic attack, or diabetes mellitus with evidence of end- organ damage. MICARDIS has been used with other required treatment such as other antihypertensives (including ACEI), antiplatelet or statins (see 7 WARNINGS AND PRECAUTIONS, 9 DRUG INTERACTIONS and 14 CLINICAL TRIALS section).

Treatment of essential hypertension. 5 mg hydrochlorothiazide) is indicated in adults whose blood pressure is not adequately controlled on telmisartan alone.

1 INDICATIONS AND USAGE Telmisartan tablets, USP are an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

1 Hypertension Telmisartan tablets, USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake.