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AG-DOXYCYCLINE is a brand name for Doxycycline, supplied as a tablet. The medicine, its uses, side effects and dosage are the same regardless of brand.
Verbatim from this product's HC label. Tap a section to expand.
DOSAGE EXCEEDING THE RECOMMENDED DOSAGE MAY RESULT IN AN INCREASED INCIDENCE OF SIDE EFFECTS. Adults The recommended dosage of AG-Doxycycline for the majority of susceptible infections is a single loading dose of 200 mg on the first day of treatment followed by a maintenance dosage of 100 mg once daily at the same time each day thereafter.
In the management of more severe infections (particularly chronic infections of the urinary tract), 200 mg should be given daily throughout the treatment period. Therapy should be continued for at least 24-48 hours after symptoms and fever have subsided.
It should be noted, however, that effective antibacterial levels are usually present 24 to 36 hours following discontinuance of doxycycline hyclate therapy. When used in streptococcal infections, therapy should be continued for 10 days to prevent the development of rheumatic fever or glomerulonephritis.
d. for 3 days. For treatment of uncomplicated urethral, endocervical, or vaginal infections in adults associated with Chlamydia trachomatis and Ureaplasma urealyticum: 100 mg, by mouth, twice a day for at least 10 days. No alteration in recommended dosage schedule need be made when treating patients with impaired renal function.
ADMINISTRATION AG-Doxycycline should be given with or after a meal in order to minimize the possibility of gastric upset. Antacids and iron preparations impair absorption and should not be given concomitantly to patients taking oral doxycycline hyclate.
Patients should be advised to take AG-Doxycycline with a full glass of water, to keep in orthostatic position after the administration and not to go to bed within 1-2 hours after the intake. Prescribing Information AG-Doxycycline (Doxycycline Hyclate Tablets, USP) Page 12 of 26 ` PHARMACEUTICAL INFORMATION CHEMISTRY Proper Name: Doxycycline Hyclate Chemical Name: 2-Naphthacenecarboxamide, 4-(dimethyIamino)-1,4,4a,5,5a,6,11,12a octahydro-3,5,10,12,12a-pentahydroxy-6- methyl-1,11-dioxo- monohydrochloride, compd.
9 g/mol Description: Doxycycline hyclate is a yellow crystalline powder. It is freely soluble in water and in methanol, sparingly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and carbonates.
Composition:
AG-Doxycycline contain doxycycline hyclate equivalent to 100 mg of doxycycline.
Non-medicinal ingredients:
Colloidal silicon dioxide, D&C Yellow No. 10, FD&C blue No. 2, FD&C Yellow No. 6, FD&C Red No. 40, hypromellose, macrogol, magnesium stearate, microcrystalline cellulose, pregelatinized starch, polysorbate 80, sodium starch glycolate, stearic acid and titanium dioxide.
DOSAGE FORMS AVAILABILITY AG-Doxycycline:
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
Orange, round, bi-convex film-coated tablets, engraved with 'DOXY 100' on one side and 'JP' separated by a score line on the other side. Available in bottles of 100 and 250 tablets. Prescribing Information AG-Doxycycline (Doxycycline Hyclate Tablets, USP) Page 13 of 26 ` STORAGE Bottles of AG-Doxycycline (doxycycline hyclate) 100 mg should be stored at controlled room temperature 15-30°C.
Protect from light and excessive humidity. Keep out of reach and sight of children. MICROBIOLOGY Doxycycline is a broad-spectrum antibiotic and has been shown to be active in vitro against the following Gram-negative, Gram-positive and other micro-organisms: Staphylococcus aureus Bacillus subtilis Staphylococcus epidermidis (albus) Neisseria gonorrhoeae Streptococcus pyogenes Neisseria catarrhalis Streptococcus faecalis Escherichia coli Streptococcus pneumoniae Enterobacter aerogenes Streptococcus viridans Pseudomonas aeruginosa Listeria monocytogenes Haemophilus influenzae Klebsiella pneumoniae Serratia spp.
Salmonella typhi Brucella spp Salmonella typhimurium Proteus spp. Salmonella enteriditis Pasteurella spp Shigella sonnei Mycoplasma pneumoniae Shigella flexneri Chlamydia trachomatis Corynebacterium diphtheriae Ureaplasma urealyticum Bacillus anthracis The drugs in the tetracycline class have closely similar antimicrobial spectra, and cross- resistance among them is common.
SUSCEPTIBILITY TESTING The Kirby-Bauer method of disc susceptibility testing (using the 30 mcg doxycycline disc) and dilution susceptibility should be interpreted according to the criteria in TABLE 1. C. ) was conducted in normal, healthy, adult male subjects under fed conditions.
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