Sodium Nitrite
Antidotes
- Drug class
- Antidotes
- Availability
- See label
- Routes
- Intravenous
- Markets covered
- 2
- Products on record
- 3
Overview
Sodium Nitrite is an active pharmaceutical ingredient in the Antidotes group (V03AB). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 2 | February 20, 2026 |
| CA Canada | Health Canada | 1 | March 22, 2025 |
GBUnited Kingdom· MHRA
2 products
Uses
Sodium nitrite is indicated for sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening. When the diagnosis of cyanide poisoning is uncertain, the potentially life- threatening risks associated with sodium nitrite should be carefully weighed against the potential benefits, especially if the patient is not in extremis.
4). Consideration should be given to official guidelines for the treatment of cyanide intoxication.
How to take
CACanada· Health Canada
1 product
Uses
18 Page 3 of 22 SODIUM NITRITE INJECTION, USP 30 mg/mL PART I: HEALTH PROFESSIONAL INFORMATION HEALTH CANADA HAS AUTHORIZED THE SALE OF THIS EXTRAORDINARY USE NEW DRUG FOR THE TREATMENT OF CYANIDE POISONING THAT IS JUDGED TO BE LIFE-THREATENING BASED ON LIMITED CLINICAL TESTING IN HUMANS SUMMARY PRODUCT INFORMATION Route of Administration Dosage Form / Strength Clinically Relevant Nonmedicinal Ingredients Intravenous Sodium nitrite injection, USP, 30 mg/mL None For a complete listing see Dosage Forms, Composition and Packaging section.
INDICATIONS AND CLINICAL USE Sodium Nitrite Injection is indicated for sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening. When the diagnosis of cyanide poisoning is uncertain, the potential risks associated with Sodium Nitrite Injection should be carefully weighed against the potential benefits, especially if the patient is not in extremis.
Cyanide poisoning may result from inhalation, ingestion, or dermal exposure to various cyanide- containing compounds, including smoke from closed-space fires. Sources of cyanide poisoning include hydrogen cyanide and its salts, cyanogenic plants, aliphatic nitriles, and prolonged exposure to sodium nitroprusside.
Sources & citations
- [1]MHRA (UK) · PL425890001 · revised January 23, 2026
- [2]Health Canada (DPD) · 02440466 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.