Sodium Chloride
Active ingredient · 3 therapeutic classes
Sold as SSP+ · Saline · Ringers · Licefreee · Aqua marina
- Drug class
- Sodium
- Availability
- Prescription and OTC
- Routes
- Intravenous, Intraperitoneal, Haemodialysis, Extracorporeal, Subcutaneous
- Markets covered
- 3
- Products on record
- 300
- FDA reports (12 mo)
- 20,464
Overview
Plain-language summary, compiled from the cited regulatory records
Sodium Chloride is an electrolyte solution classified as Sodium (A12CA) [1]. This sterile, nonpyrogenic solution is approved for general irrigation, washing, rinsing, and dilution purposes [1]. It is also indicated for blood cell washing when used with automated intraoperative blood salvaging equipment [1].
This active ingredient is available under various brand names, including Ringers, BHI Constipation, and Family Care Saline [1]. In the past 12 months, there have been 20,464 adverse event reports associated with products containing Sodium Chloride [2]. The most frequently reported reactions in this period include off-label use, reports of the drug being ineffective, nausea, fatigue, and myelosuppression [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 181 | May 29, 2026 |
| GB United Kingdom | MHRA | 80 | May 29, 2026 |
| US United States | FDA | 39 | April 1, 2026 |
CACanada· Health Canada
181 products
Uses
9% Sodium Chloride USP is indicated for use in adults and pediatric patients as sources of electrolytes and water for hydration. 9% Sodium Chloride USP is also indicated as pharmaceutic aids and diluents for the infusion of compatible drug additives.
Refer to prescribing information accompanying additive drugs. 9% Sodium Chloride Injection USP is indicated for extracellular fluid replacement, treatment of metabolic alkalosis in the presence of fluid loss and mild sodium depletion.
9% Sodium Chloride Injection USP is also indicated for use as a priming solution in hemodialysis procedures and may be used to initiate and terminate blood transfusions without hemolyzing red blood cells. 1 Pediatrics Pediatrics (<16 years of age): For considerations of the safe use in pediatric patients, see Warnings and Precautions, Special Populations, Pediatrics.
2 Geriatrics Geriatrics (>65 years of age): For considerations of the safe use in geriatric patients, see Warnings and Precautions, Special Populations, Geriatrics.
GBUnited Kingdom· MHRA
80 products
Uses
9% solution for infusion is indicated for: - Treatment of isotonic extracellular dehydration - Treatment of sodium depletion - Vehicle or diluent of compatible drugs for parenteral administration.
How to take
USUnited States· FDA
39 products
Uses
INDICATIONS AND USAGE
This sterile, nonpyrogenic electrolyte solution is indicated for all general irrigation, washing, rinsing and dilution purposes including blood cell washing (when used in conjunction with automated intraoperative blood salvaging equipment).
How to take
Drug interactions
Known interactions involving Sodium Chloride. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 01924303 · revised March 22, 2025
- [2]MHRA (UK) · PL438170001 · revised March 28, 2025
- [3]FDA DailyMed · 009bef3c-e8ac-46… · revised October 31, 2025 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.