Magnesium Sulfate
Active ingredient · 5 therapeutic classes
Sold as Epsom Salt
- Drug class
- Osmotically Acting Laxatives
- Availability
- Over-the-counter
- Routes
- Intramuscular, Intravenous, Oral, Topical
- Markets covered
- 3
- Products on record
- 14
- FDA reports (12 mo)
- 933
Overview
Plain-language summary, compiled from the cited regulatory records
Magnesium Sulfate is an active ingredient classified as an osmotically acting laxative [1]. It is approved for use in preventing cramps and spasms, releasing muscle tightness, and relieving muscle soreness [1]. This ingredient is available under various brand names, including Epsom Salt [1].
In the past 12 months, there have been 933 adverse event reports associated with Magnesium Sulfate [2]. The most frequently reported reactions include vomiting, nausea, and cases where the drug was reported as ineffective [2]. Additionally, reports have noted maternal exposure during pregnancy and off-label use [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 7 | April 22, 2026 |
| US United States | FDA | 4 | February 9, 2026 |
| GB United Kingdom | MHRA | 3 | April 10, 2026 |
CACanada· Health Canada
7 products
Uses
Magnesium Sulfate Injection USP (magnesium sulfate injection) may be of therapeutic value in the following conditions: • as an anticonvulsant, for preeclampsia and eclampsia of pregnancy; • as an electrolyte replenisher for hypomagnesemia and magnesium deficiency to maintain normal neuromuscular irritability.
1 Pediatrics Pediatrics (<18 years of age): Health Canada has not authorized an indication for pediatric use. 3 Pediatrics). 2 Geriatrics Geriatrics: Health Canada has not authorized an indication for geriatric use. 4 Geriatrics).
How to take
USUnited States· FDA
4 products
Uses
Uses relieves occasional constipation (irregularity) generally produces bowel movement in 1/2 to 6 hours
How to take
GBUnited Kingdom· MHRA
3 products
Uses
Treatment of magnesium deficiency in hypomagnesaemia where the oral route of administration may be inappropriate. To prevent further seizures associated with eclampsia.
How to take
Drug interactions
Known interactions involving Magnesium Sulfate. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 02562235 · revised April 22, 2026
- [2]FDA DailyMed · 1845ea0c-0cb6-48… · revised February 9, 2026 [PDF]
- [3]MHRA (UK) · PL120640048 · revised April 10, 2026
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.