Neostigmine
Active ingredient · 2 therapeutic classes
- Drug class
- Anticholinesterases
- Availability
- Prescription only
- Routes
- Intravenous, Subcutaneous
- Markets covered
- 3
- Products on record
- 12
Overview
Plain-language summary, compiled from the cited regulatory records
Neostigmine is a medication classified as an anticholinesterase [1]. It functions by inhibiting the breakdown of acetylcholine, a neurotransmitter, thereby increasing its levels in the body [1].
Neostigmine methylsulfate injection is approved for reversing the effects of nondepolarizing neuromuscular blocking agents (NMBAs) after surgical procedures [1]. These blocking agents are often used during surgery to relax muscles. Neostigmine helps to restore normal muscle function by counteracting their effects [1].
While neostigmine is available under various brand names, specific examples were not provided in the source data. There were no adverse event reports within the last 12 months noted in the provided data.
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| US United States | FDA | 4 | March 5, 2024 |
| GB United Kingdom | MHRA | 1 | May 15, 2026 |
| CA Canada | Health Canada | 7 | March 22, 2025 |
USUnited States· FDA
4 products
Uses
1 INDICATIONS AND USAGE Neostigmine Methylsulfate Injection, a cholinesterase inhibitor, is indicated for reversal of the effects of nondepolarizing neuromuscular blocking agents (NMBA) after surgery. Neostigmine Methylsulfate, a cholinesterase inhibitor, is indicated for reversal of the effects of nondepolarizing neuromuscular blocking agents (NMBA) after surgery ( 1 ).
How to take
GBUnited Kingdom· MHRA
1 product
Uses
Myasthenia Gravis, antagonist to non-depolarizing neuromuscular blockade, Paralytic Ileus, Post-operative Urinary Retention; Paroxysmal Supraventricular Tachycardia.
How to take
CACanada· Health Canada
7 products
7 products on record with this regulator. Detailed label text (uses, dosage, side effects) is being ingested — the original document is linked under Sources [3].
Drug interactions
Known interactions involving Neostigmine. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]FDA DailyMed · 088f96eb-20b8-48… · revised January 22, 2024 [PDF]
- [2]MHRA (UK) · PL015020023 · revised May 15, 2026
- [3]Health Canada (DPD) · 02230592 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.