Pilocarpine
Active ingredient · 2 therapeutic classes
- Drug class
- Other Parasympathomimetics
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 3
- Products on record
- 15
Overview
Pilocarpine is an active pharmaceutical ingredient in the Other Parasympathomimetics group (N07AX). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 12 | May 1, 2026 |
| US United States | FDA | 2 | December 12, 2024 |
| CA Canada | Health Canada | 1 | March 22, 2025 |
GBUnited Kingdom· MHRA
12 products
Uses
1. Alleviation of symptoms of salivary gland hypofunction in patients with severe xerostomia following irradiation for head and neck cancer. 2. Treatment of symptoms of dry mouth and dry eyes in patients with Sjögren’s syndrome.
How to take
USUnited States· FDA
2 products
Uses
INDICATIONS AND USAGE:
Pilocarpine hydrochloride tablets, USP are indicated for 1) the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of the head and neck; and 2) the treatment of symptoms of dry mouth in patients with Sjogren's syndrome.
How to take
CACanada· Health Canada
1 product
Uses
31 PILOCARPINE HYDROCHLORIDE TABLETS Product Monograph Page 3 of 33 PrPILOCARPINE HYDROCHLORIDE TABLETS PART I: HEALTH PROFESSIONAL INFORMATION SUMMARY PRODUCT INFORMATION INDICATIONS AND CLINICAL USE PILOCARPINE HYDROCHLORIDE TABLETS is indicated for: the treatment of the symptoms of xerostomia (dry mouth) due to salivary gland hypofunction caused by radiotherapy for cancer of the head and neck, the treatment of the symptoms of xerostomia (dry mouth) and xerophthalmia (dry eyes) in patients with Sjögren's syndrome.
Pediatrics (< 18 years of age):
Safety and effectiveness of PILOCARPINE HYDROCHLORIDE TABLETS have not been studied in children under 18 years of age. Route of Administration Dosage Form / Strength Clinically Relevant Nonmedicinal Ingredients oral tablet 5 mg carnauba wax, hypromellose, microcrystalline cellulose, polyethylene glycol, polysorbate 80, stearic acid, titanium dioxide For a complete listing see Dosage Forms, Composition and Packaging section.
Drug interactions
Known interactions involving Pilocarpine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 271. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL201170404 · revised March 13, 2026
- [2]FDA DailyMed · 06c054af-62b4-43… · revised December 12, 2024 [PDF]
- [3]Health Canada (DPD) · 02506580 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.