Pyridostigmine
Anticholinesterases
- Drug class
- Anticholinesterases
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 2
- Products on record
- 8
Overview
Plain-language summary, compiled from the cited regulatory records
Pyridostigmine is an anticholinesterase medication [1]. It is used to treat myasthenia gravis [1]. Myasthenia gravis is a condition that causes weakness in the voluntary muscles [1].
Pyridostigmine is available in tablet form [1]. It works by increasing the levels of a chemical messenger in the muscles, which helps to improve muscle strength and reduce fatigue [1]. This medication is part of the anticholinesterase drug class [1].
This active ingredient is sold under several brand names [1]. There were no adverse event reports for this ingredient in the last 12 months [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| US United States | FDA | 4 | December 23, 2025 |
| GB United Kingdom | MHRA | 4 | November 10, 2025 |
USUnited States· FDA
4 products
Uses
1 INDICATIONS AND USAGE Pyridostigmine bromide is indicated for pretreatment against the lethal effects of soman nerve agent poisoning in adults. Pyridostigmine bromide is intended for use in conjunction with protective garments, including a mask.
At the first sign of nerve agent poisoning, pyridostigmine bromide should be stopped, and atropine and pralidoxime therapy started immediately. The evidence for the effectiveness of pyridostigmine bromide as pretreatment against soman-induced toxicity was derived from animal studies alone [see Clinical Studies (14) ] .
FOR MILITARY MEDICAL USE ONLY Pyridostigmine bromide is a cholinesterase inhibitor indicated for pretreatment against the lethal effects of soman nerve agent poisoning in adults. ( 1 ) Pyridostigmine bromide is for use in conjunction with: Protective garments, including a gas mask, and Immediate atropine and pralidoxime therapy at the first sign of nerve agent poisoning.
GBUnited Kingdom· MHRA
4 products
Uses
Myasthenia gravis, paralytic ileus and post-operative urinary retention.
How to take
Drug interactions
Known interactions involving Pyridostigmine. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]FDA DailyMed · 0b296555-c32f-42… · revised December 23, 2025 [PDF]
- [2]MHRA (UK) · PL002892298 · revised September 12, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.