Eptifibatide
Platelet Aggregation Inhibitors Excl. Heparin
Sold as Integrilin
- Drug class
- Platelet Aggregation Inhibitors Excl. Heparin
- Availability
- Prescription only
- Routes
- Intravenous
- Markets covered
- 4
- Products on record
- 14
- FDA reports (12 mo)
- 11
Overview
Eptifibatide is an active pharmaceutical ingredient in the Platelet Aggregation Inhibitors Excl. Heparin group (B01AC). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 6 | June 2, 2026 |
| GB United Kingdom | MHRA | 6 | May 1, 2026 |
| US United States | FDA | 1 | January 4, 2024 |
| EU European Union | EMA | 1 | May 2, 2025 |
CACanada· Health Canada
6 products
How to take
Eptifibatide Injection solution for injection must always be given as an intravenous bolus followed by the Eptifibatide Injection solution for infusion. 0 mcg/kg/min until hospital discharge or initiation of CABG surgery, up to 72 hours.
If a patient undergoes PCI, Eptifibatide Injection infusion should be continued until hospital discharge or for up to 18-24 hours after the procedure, whichever comes first, allowing for 96 hours of therapy. 75 mg/mL injection) per hour.
0 mcg/kg/min. 75 mg/mL injection) per hour. 0 mcg/kg/min and a second 180 mcg/kg bolus 10 minutes after the first bolus. Infusion should be continued until hospital discharge or for up to 18-24 hours, whichever comes first. A minimum of 12 hours of infusion is recommended.
75 mg/mL injection) per hour. The recommended adult dose of eptifibatide in patients with moderate renal impairment (creatinine clearance of ≥30 -<50 mL/min, using the Cockcroft-Gault* equation), is an intravenous bolus of 180 mcg/kg administered immediately before the initiation of the procedure, followed by a second 180 mcg/kg bolus administered 10 minutes after the first bolus injection.
GBUnited Kingdom· MHRA
6 products
Uses
Eptifibatide Accord is intended for use with acetylsalicylic acid and unfractionated heparin. Eptifibatide Accord is indicated for the prevention of early myocardial infarction in adults presenting with unstable angina or non-Q-wave myocardial infarction, with the last episode of chest pain occurring within 24 hours and with electrocardiogram (ECG) changes and/or elevated cardiac enzymes.
1).
How to take
USUnited States· FDA
1 product
Uses
1 Acute Coronary Syndrome (ACS) Eptifibatide injection is indicated to decrease the rate of a combined endpoint of death or new myocardial infarction (MI) in patients with ACS (unstable angina [UA]/non-ST-elevation myocardial infarction [NSTEMI]), including patients who are to be managed medically and those undergoing percutaneous coronary intervention (PCI).
2) ] .
How to take
EUEuropean Union· EMA
1 product
Uses
Eptifibatide Accord is intended for use with acetylsalicylic acid and unfractionated heparin. Eptifibatide Accord is indicated for the prevention of early myocardial infarction in adults presenting with unstable angina or non-Q-wave myocardial infarction, with the last episode of chest pain occurring within 24 hours and with electrocardiogram (ECG) changes and/or elevated cardiac enzymes.
1).
How to take
Drug interactions
Known interactions involving Eptifibatide. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 02422840 · revised March 22, 2025
- [2]MHRA (UK) · PLGB200751276 · revised May 1, 2026
- [3]FDA DailyMed · 00ad7bbe-cadd-46… · revised January 4, 2024 [PDF]
- [4]European Medicines Agency · EMEA/H/C/004104 · revised May 2, 2025
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.