Dipyridamole
Platelet Aggregation Inhibitors Excl. Heparin
Sold as PERSANTINE
- Drug class
- Platelet Aggregation Inhibitors Excl. Heparin
- Availability
- Prescription only
- Routes
- Intravenous, Oral
- Markets covered
- 3
- Products on record
- 16
- FDA reports (12 mo)
- 71
Overview
Plain-language summary, compiled from the cited regulatory records
Dipyridamole is a medication classified as a platelet aggregation inhibitor [1]. It is used as an add-on therapy to coumarin anticoagulants to help prevent blood clots that can occur after heart valve replacement surgery [1].
In the past 12 months, there were 71 adverse event reports associated with dipyridamole [2]. The most frequently reported adverse events include off-label use, toxicity from various agents, difficulty breathing (dyspnoea), low blood pressure (hypotension), and falls [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 13 | May 15, 2026 |
| CA Canada | Health Canada | 2 | March 22, 2025 |
| US United States | FDA | 1 | September 16, 2023 |
GBUnited Kingdom· MHRA
13 products
Uses
1. As an adjunct to oral anti-coagulation for prophylaxis of thromboembolism associated with prosthetic heart valves. 2. In combination with aspirin for: a. Prophylaxis of deep venous thrombosis as an alternative to subcutaneous heparin, other than in hip surgery.
b. Prophylaxis of recurrent venous thrombosis resistant to oral anti- coagulation. c. Prophylaxis of occlusion following prosthetic arterial grafts and coronary artery bypass grafts.
How to take
CACanada· Health Canada
2 products
Uses
PERSANTINE (5 mg/mL dipyridamole) is indicated for: • intravenous use to induce pharmacologic vasodilation for myocardial perfusion imaging. 1 Pediatrics Pediatrics (< 18 years of age): No data are available to Health Canada; therefore, Health Canada has not authorized an indication for pediatric use.
How to take
USUnited States· FDA
1 product
Uses
INDICATIONS AND USAGE
Dipyridamole tablets are indicated as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement.
How to take
Drug interactions
Known interactions involving Dipyridamole. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 293. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL334140042 · revised November 21, 2025
- [2]Health Canada (DPD) · 00637734 · revised March 22, 2025
- [3]FDA DailyMed · 004bada0-dbf7-4a… · revised September 16, 2023 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.