Ciprofloxacin
Active ingredient · 4 therapeutic classes
Sold as OTIXAL · CILOXAN · CIPRODEX · APO-CIPROFLOX · CIRPROFLOXACIN
- Drug class
- Fluoroquinolones
- Availability
- Prescription only
- Routes
- Intravenous, Oral, Ophthalmic, Otic, Auricular (Otic)
- Markets covered
- 3
- Products on record
- 170
- FDA reports (12 mo)
- 3,770
Overview
Ciprofloxacin is an active pharmaceutical ingredient in the Fluoroquinolones group (J01MA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 89 | May 22, 2026 |
| CA Canada | Health Canada | 54 | June 1, 2026 |
| US United States | FDA | 27 | May 13, 2026 |
GBUnited Kingdom· MHRA
89 products
Uses
8) this product must only be prescribed when other antibiotics that are commonly recommended for the infection are inappropriate. This applies to all indications listed below. Situations where other antibiotics are considered to be inappropriate are where: • there is resistance to other first-line antibiotics recommended for the infection; • other first-line antibiotics are contraindicated in an individual patient; • other first-line antibiotics have caused side effects requiring treatment to be stopped; treatment with other first-line antibiotics has failed.
g. lobar and bronchopneumonia, acute and chronic bronchitis, acute exacerbation of cystic fibrosis, bronchiectasis, empyema. Ciprofloxacin is not recommended as first-line therapy for the treatment of pneumococcal pneumonia. Ciprofloxacin may be used for treating Gram-negative pneumonia.
g. ). Ciprofloxacin is not recommended for the treatment of acute tonsillitis. g. bacterial conjunctivitis. g. uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis, epididymitis. g. infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas, infected burns.
CACanada· Health Canada
54 products
Uses
pms-CIPROFLOXACIN (ciprofloxacin tablets) may be indicated for the treatment of patients with the following infections caused by susceptible strains of the indicated microorganisms: Respiratory Tract Infections Acute exacerbation of chronic bronchitis caused by: Haemophilus influenzae Moraxella catarrhalis Acute pneumonia caused by: Enterobacter cloacae Escherichia coli Haemophilus influenzae Klebsiella pneumoniae Proteus mirabilis Pseudomonas aeruginosa Staphylococcus aureus Acute sinusitis caused by: Haemophilus influenzae Moraxella catarrhalis pms-CIPROFLOXACIN should not be prescribed to patients with acute bacterial exacerbations of simple / uncomplicated chronic obstructive pulmonary disease (ie.
1 pms-CIPROFLOXACIN are not indicated for acute bronchitis. Due to the nature of the underlying conditions which usually predispose patients to pseudomonas infections of the respiratory tract, bacterial eradications may not be achieved in patients who display clinical improvement despite evidence of in vitro sensitivity.
USUnited States· FDA
27 products
Uses
INDICATIONS AND USAGE
Ciprofloxacin Ophthalmic Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below: Corneal Ulcers: Pseudomonas aeruginosa Serratia marcescens * Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae Streptococcus (Viridans Group) * Conjunctivitis: Haemophilus influenzae Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae *Efficacy for this organism was studied in fewer than 10 infections.
How to take
Drug interactions
Known interactions involving Ciprofloxacin. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 600. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL183740004 · revised December 15, 2023
- [2]Health Canada (DPD) · 02248436 · revised March 22, 2025
- [3]FDA DailyMed · 05b2836d-cd3d-4d… · revised May 2, 2022 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.