MOVICOL LIQUID ORANGE FLAVOUR

Posology A course of treatment for constipation with Movicol Liquid Orange flavour does not normally exceed 2 weeks, although this can be repeated if required. As for all laxatives, prolonged use is not usually recommended. Extended use may be necessary in the care of patients with severe chronic or resistant constipation, secondary to multiple sclerosis or Parkinson’s Disease, or induced by regular constipating medication in particular opioids and antimuscarinics.

Adults, adolescents and older people: 25 ml diluted in 100 ml of water 1-3 times daily in divided doses, according to individual response. For extended use, the dose can be adjusted down to 1 or 2 doses per day of 25 ml diluted in 100 ml of water.

Children:

Movicol Liquid Orange flavour is not recommended for use in children below the age of 12 years. Alternative Movicol products are available for children. 4 for warning about excipients). 4). Alternative Movicol products are available for the treatment of faecal impaction.

Method of administration The product must not be taken undiluted and may only be diluted in water. 6.

8. g. oedema, shortness of breath, increasing fatigue, dehydration, cardiac failure), Movicol Liquid Orange flavour should be stopped immediately and electrolytes measured and any abnormality should be treated appropriately. 5). 125 mmol of sodium in each diluted dose of 125 ml.

The sodium content of Movicol Liquid Orange flavour should be taken into consideration when administering the product to patients on a controlled sodium diet. 825 mg/ml. Benzyl alcohol may cause anaphylactoid reactions. High volumes of benzyl alcohol should be used with caution and only if necessary, especially in subjects with kidney or liver impairment and during pregnancy/breast feeding because of the risk of accumulation and toxicity (metabolic acidosis) of benzyl alcohol.

0 mg of ethanol per mL. The amount in 25 mL concentrate for oral solution of this medicine is equivalent to less than 2 mL of beer or 1 mL of wine. The small amount of alcohol in this medicine will not have any noticeable effects. This product contains ethyl (E214) and methyl (E218) parahydroxybenzoates which may cause allergic reactions, possibly delayed.

3% of the WHO recommended maximum daily intake for sodium. When used long term for constipation, the maximum daily dose of this product is equivalent to 28% of the WHO recommended maximum daily intake for sodium. Movicol Liquid Orange flavour is considered high in sodium.

This should be particularly taken into account for those on a low salt diet. 5. 5 Interaction with other medicinal products and other forms of interaction Macrogol raises the solubility of medicinal products that are soluble in alcohol and relatively insoluble in water.

4). g. anti-epileptics. Therefore, other medicines should not be taken orally for one hour before, during and for one hour after taking Movicol Liquid Orange flavour. Movicol Liquid Orange flavour may result in a potential interactive effect if used with starch-based food thickeners.

The Macrogol ingredient counteracts the thickening effect of starch, effectively liquefying preparations that need to remain thick for people with swallowing problems. 6 Fertility, pregnancy and lactation Pregnancy There are limited amount of data from the use of Movicol in pregnant women.

3). Clinically, no effects during pregnancy are anticipated, since systemic exposure to macrogol 3350 is negligible. Movicol can be used during pregnancy. Breastfeeding No effects on the breastfed newborn/infant are anticipated since the systemic exposure of the breast-feeding woman to Macrogol 3350 is negligible.

Movicol can be used during breast-feeding. Fertility There are no data on the effects of Movicol on fertility in humans. 3). 7 Effects on ability to drive and use machines Movicol Liquid Orange flavour has no influence on the ability to drive and use machines.

8 Undesirable effects Reactions related to the gastrointestinal tract occur most commonly. These reactions may occur as a consequence of expansion of the contents of the gastrointestinal tract, and an increase in motility due to the pharmacologic effects of Movicol Liquid Orange flavour.

Mild diarrhoea usually responds to dose reduction. The frequency of the adverse events is not known as it cannot be estimated from the available data. System Organ Class Adverse Event Immune system disorders Allergic reactions, including anaphylactic reaction, dyspnoea and skin reactions (see below) Skin and subcutaneous tissue disorders Allergic skin reactions including angioedema, urticaria, pruritus, rash, erythema Metabolism and nutrition disorders Electrolyte disturbances, particularly hyperkalaemia and hypokalaemia.

Nervous system disorders Headache Gastrointestinal disorders Abdominal pain, diarrhoea, vomiting, nausea, dyspepsia, abdominal distension, borborygmi, flatulence and anorectal discomfort. General disorders and administration site conditions Peripheral oedema Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.

It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

The fluid content of Movicol Liquid Orange flavour when re-constituted with water does not replace regular fluid intake and adequate fluid intake must be maintained. 8. g. oedema, shortness of breath, increasing fatigue, dehydration, cardiac failure), Movicol Liquid Orange flavour should be stopped immediately and electrolytes measured and any abnormality should be treated appropriately.

5). 125 mmol of sodium in each diluted dose of 125 ml. The sodium content of Movicol Liquid Orange flavour should be taken into consideration when administering the product to patients on a controlled sodium diet. 825 mg/ml. Benzyl alcohol may cause anaphylactoid reactions.

High volumes of benzyl alcohol should be used with caution and only if necessary, especially in subjects with kidney or liver impairment and during pregnancy/breast feeding because of the risk of accumulation and toxicity (metabolic acidosis) of benzyl alcohol.

0 mg of ethanol per mL. The amount in 25 mL concentrate for oral solution of this medicine is equivalent to less than 2 mL of beer or 1 mL of wine. The small amount of alcohol in this medicine will not have any noticeable effects. This product contains ethyl (E214) and methyl (E218) parahydroxybenzoates which may cause allergic reactions, possibly delayed.

3% of the WHO recommended maximum daily intake for sodium. When used long term for constipation, the maximum daily dose of this product is equivalent to 28% of the WHO recommended maximum daily intake for sodium. Movicol Liquid Orange flavour is considered high in sodium.

This should be particularly taken into account for those on a low salt diet. 5.

Intestinal perforation or obstruction due to structural or functional disorder of the gut wall, ileus, severe inflammatory conditions of the intestinal tract, such as Crohn’s disease and ulcerative colitis and toxic megacolon. 1.