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🏠›Trazodone›Interaction with Diphenhydramine

Trazodone + Diphenhydramine

Drug interaction

Moderate interaction

A moderate drug-drug interaction between Trazodone and Diphenhydramine is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “moderate” means

A moderate interaction can matter in some people. The combination is sometimes used, but usually with caution - monitoring, timing changes, or dose adjustments.

What to do

Mention this combination to your pharmacist or prescriber. Do not stop either medicine without advice.

The two medicines

Active ingredient

Trazodone

Other Antidepressants

Uses, side effects, dosage →· 667 recorded interactions

Active ingredient

Diphenhydramine

Antihistamines For Topical Use

Uses, side effects, dosage →· 368 recorded interactions

Source

DDInter 2.0 (CC-BY 4.0, https://ddinter.scbdd.com)

This is not medical advice. Drugvu is an independent aggregator of public records.

Trazodone and Diphenhydramine: Moderate Interaction - Drugvu