Labetalol + Tizanidine

Drug interaction

Major interaction

A major drug-drug interaction between Labetalol and Tizanidine is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “major” means

A major interaction can cause a clinically significant - sometimes serious - effect. Prescribers usually avoid this combination, or use it only with close monitoring and dose adjustments.

What to do

Do not combine these on your own. If both have been prescribed, tell your pharmacist or doctor so they can confirm it is intended and watch for problems.

Side effects reported for both

Labetalol and Tizanidine are each reported to cause the effects below. Taking them together can make these more likely or more pronounced - one of the ways a drug interaction matters.

NauseaHeadacheDizzinessDyspnoea

Compiled from public adverse-event reports; an overlap, not a confirmed causal mechanism.

The two medicines

Active ingredient

Labetalol

Alpha and Beta Blocking Agents

Uses, side effects, dosage →· 527 recorded interactions

Active ingredient

Tizanidine

Other Centrally Acting Agents

Uses, side effects, dosage →· 650 recorded interactions

Source

DDInter 2.0 (CC-BY 4.0, https://ddinter.scbdd.com)

This is not medical advice. Drugvu is an independent aggregator of public records.