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🏠›Amitriptyline›Interaction with Diphenhydramine

Amitriptyline + Diphenhydramine

Drug interaction

Moderate interaction

A moderate drug-drug interaction between Amitriptyline and Diphenhydramine is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “moderate” means

A moderate interaction can matter in some people. The combination is sometimes used, but usually with caution - monitoring, timing changes, or dose adjustments.

What to do

Mention this combination to your pharmacist or prescriber. Do not stop either medicine without advice.

The two medicines

Active ingredient

Amitriptyline

Non-Selective Monoamine Reuptake Inhibitors

Uses, side effects, dosage →· 703 recorded interactions

Active ingredient

Diphenhydramine

Antihistamines For Topical Use

Uses, side effects, dosage →· 368 recorded interactions

Source

DDInter 2.0 (CC-BY 4.0, https://ddinter.scbdd.com)

This is not medical advice. Drugvu is an independent aggregator of public records.

Amitriptyline and Diphenhydramine: Moderate Interaction - Drugvu