Trimeprazine
Phenothiazine Derivatives
Sold as PANECTYL · ALIMEMAZINE TARTRATE
- Drug class
- Phenothiazine Derivatives
- Availability
- See label
- Routes
- Oral
- Markets covered
- 2
- Products on record
- 26
Overview
Trimeprazine is an active pharmaceutical ingredient in the Phenothiazine Derivatives group (R06AD). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 24 | May 15, 2026 |
| CA Canada | Health Canada | 2 | March 22, 2025 |
GBUnited Kingdom· MHRA
24 products
Uses
Alimemazine has powerful antihistamine and anti-emetic actions and is used for the management of urticaria and pruritus. Alimemazine tartrate 10mg/5ml oral solution, sugar-free should be used for this indication in children. 2).
How to take
CACanada· Health Canada
2 products
Who should not take it
States of CNS depression due to barbiturates, alcohol, narcotics or analgesics. Cases with a history of blood dyscrasias or severe allergic reactions related to trimeprazine or other phenothiazines. Trimeprazine is contraindicated for use in children less than two years of age.
(see Warnings section). WARNINGS Patients should be advised against driving or engaging in activities requiring complete mental alertness or physical co-ordination, until their response to the drug has been well established. Use in pregnant women is not recommended except when, in the judgement of the physician, it is necessary for the welfare of the patient.
Trimeprazine is contraindicated for use in children less than two years of age due to the risk of marked sedation and respiratory depression. Cardiac arrhythmias and ECG abnormalities Atrioventricular (AV) block, supraventricular tachycardia, ventricular tachycardia and fibrillation have been reported during therapy, possibly related to dosage.
Drug interactions
Known interactions involving Trimeprazine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 527. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL004270336 · revised September 26, 2025
- [2]Health Canada (DPD) · 01926292 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.