Tenecteplase
Enzymes
Sold as Metalyse · TNKASE
- Drug class
- Enzymes
- Availability
- See label
- Routes
- Intravenous
- Markets covered
- 3
- Products on record
- 6
Overview
Tenecteplase is an active pharmaceutical ingredient in the Enzymes group (B01AD). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 3 | September 5, 2025 |
| CA Canada | Health Canada | 2 | December 12, 2025 |
| EU European Union | EMA | 1 | November 27, 2025 |
GBUnited Kingdom· MHRA
3 products
Uses
5 hours from last known well and after exclusion of intracranial haemorrhage.
How to take
CACanada· Health Canada
2 products
How to take
4 Geriatrics 2025-10 TABLE OF CONTENTS Sections or subsections that are not applicable at the time of authorization are not listed. RECENT MAJOR LABEL CHANGES ..........................................................................................
2 TABLE OF CONTENTS ............................................................................................................ 2 PART I: HEALTH PROFESSIONAL INFORMATION ....................................................................
4 1 INDICATIONS ............................................................................................................. 1 Pediatrics................................................................................................................
2 Geriatrics ................................................................................................................ 4 2 CONTRAINDICATIONS ................................................................................................
EUEuropean Union· EMA
1 product
Uses
Metalyse is indicated in adults for the thrombolytic treatment of suspected myocardial infarction with persistent ST elevation or recent left Bundle Branch Block within 6 hours after the onset of acute myocardial infarction (AMI) symptoms.
How to take
Drug interactions
Known interactions involving Tenecteplase. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PLGB145980240 · revised September 5, 2025
- [2]Health Canada (DPD) · 02244826 · revised December 12, 2025
- [3]European Medicines Agency · EMEA/H/C/000306 · revised November 27, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.