Protein C
Enzymes
Sold as OCTAPLEX · BERIPLEX P/N 500 · BERIPLEX P/N 1000
- Drug class
- Enzymes
- Availability
- See label
- Routes
- Intravenous
- Markets covered
- 2
- Products on record
- 6
Overview
Protein C is an active pharmaceutical ingredient in the Enzymes group (B01AD). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 4 | December 17, 2025 |
| GB United Kingdom | MHRA | 2 | January 2, 2026 |
CACanada· Health Canada
4 products
Uses
octaplex® (Human Prothrombin Complex) is indicated for: • The treatment of bleeding and perioperative prophylaxis of bleeding in acquired deficiency of the prothrombin complex coagulation factors, such as deficiency caused by treatment with vitamin K antagonists, or in case of overdose of vitamin K antagonists, when rapid correction of the deficiency is required.
1 Pediatrics Paediatrics No data are available to Health Canada for pediatric use. No data are available regarding the use of octaplex® in case of perinatal bleeding due to vitamin K deficiency in the newborn or due to deficiency of factors of the prothrombin complex.
2 Geriatrics Geriatrics (> 65 years of age): Many of the patients in clinical trials with octaplex® were over the age of 65. There is no evidence to suggest that use in the geriatric population is associated with differences in safety or effectiveness.
GBUnited Kingdom· MHRA
2 products
Uses
Treatment of bleeding and perioperative prophylaxis of bleeding in acquired deficiency of the prothrombin complex coagulation factors, such as deficiency caused by treatment with vitamin K antagonists, or in case of overdose of vitamin K antagonists, when rapid correction of the deficiency is required.
- Treatment of bleeding and perioperative prophylaxis in congenital deficiency of the vitamin K dependent coagulation factors II and X when purified specific coagulation factor product is not available.
How to take
Drug interactions
Known interactions involving Protein C. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 02294664 · revised March 22, 2025
- [2]MHRA (UK) · PL106730027 · revised September 19, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.