Prednisolone

Allergy and anaphylaxis:

Bronchial asthma, drug hypersensitivity reactions, serum sickness, angioneurotic oedema, anaphylaxis, incapacitating allergies unresponsive to conventional treatment.

Arteritis/collagenosis:

Giant cell arteritis/polymyalgia rheumatica, mixed connective tissue disease, polyarteritis nodosa, polymyositis.

Blood disorders:

Haemolytic anaemia (auto-immune), leukaemia (acute and chronic lymphocytic), lymphoma, multiple myeloma, idiopathic thrombocytopenic purpura Cardiovascular disorders: Post-myocardial infarction syndrome, rheumatic fever with severe carditis Endocrine disorders: Primary and secondary adrenal insufficiency, congenital adrenal hyperplasia Gastro-intestinal disorders: regional ileitis, (Crohn's disease), ulcerative colitis, persistent coeliac syndrome (celiac disease unresponsive to gluten withdrawal), auto- immune chronic active hepatitis, multisystem disease affecting liver, biliary peritonitis Hypercalcaemia: Sarcoidosis, vitamin D excess Infections (with appropriate chemotherapy): Helminthic infestations, Herxheimer reaction, infectious mononucleosis, miliary tuberculosis, mumps orchitis (adult), tuberculous meningitis, rickettsial disease Muscular disorders: Polymyositis, dermatomyositis, Bell’s palsy Neurological disorders: Infantile spasms, Shy-Drager syndrome, sub-acute demyelinating polyneuropathy Ocular disease: Scleritis, posterior uveitis, retinal vasculitis, pseudo-tumours of the orbit, giant cell arteritis, malignant ophthalmic Graves disease Renal disorders: Lupus nephritis, acute interstitial nephritis, minimal change glomerulonephritis, nephrotic syndrome Respiratory disease: Allergic pneumonitis, asthma, occupational asthma, pulmonary aspergillosis, pulmonary fibrosis, pulmonary alveolitis, aspiration of foreign body, aspiration of stomach contents, pulmonary sarcoid, drug- induced lung disease, adult respiratory distress syndrome, spasmodic croup, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculosis chemotherapy Rheumatic disorders: Rheumatoid arthritis, polymyalgia rheumatica, juvenile chronic arthritis, systemic lupus erythematosus, dermatomyositis, mixed connective tissue disease, and psoriatic arthritis Skin disorders: Pemphigus vulgaris, exfoliative dermatitis, bullous pemphigoid, systemic lupus erythematosus, pyoderma gangrenosum Miscellaneous: Sarcoidosis, hyperpyrexia, Behçets disease, immunosuppression in organ transplantation.

INDICATIONS AND USAGE

Prednisolone acetate ophthalmic suspension 1% is indicated for the treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Management of conditions known to be responsive to prednisone or prednisolone where anti-inflammatory action or immunosuppression or adrenocortical supplementation and replacement is required. For most indications, glucocorticoid administration provides symptomatic relief, but has no effect on the underlying disease processes.

Use of these medications does not eliminate the need for other therapies that may be required. 1 Pediatrics pms-PREDNISOLONE oral solution is appropriate for pediatric usage and for those patients with difficulty swallowing solid oral dosage forms.