Dexamethasone
Active ingredient · 11 therapeutic classes
Sold as Neofordex · MAXIDEX · OZURDEX · MAXITROL · LEVODEXA
- Drug class
- Corticosteroids
- Availability
- Prescription only
- Routes
- Oral, Intra-Articular, Intralesional, Intramuscular, Intravenous
- Markets covered
- 4
- Products on record
- 119
- FDA reports (12 mo)
- 16,165
Overview
Plain-language summary, compiled from the cited regulatory records
Dexamethasone is a corticosteroid used for local oral treatment [1]. It is approved to manage severe or incapacitating allergic conditions that do not respond to conventional treatments, including asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, and serum sickness [1]. It is also indicated for certain dermatologic diseases such as bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, and severe erythema multiforme (Stevens-Johnson syndrome) [1].
Dexamethasone is available under various brand names, including Neo/Poly-B/Dex Ophth Oint [1]. In the past 12 months, there have been 16,165 adverse event reports associated with this active ingredient [2]. Common reasons for these reports include off-label use, perceived drug ineffectiveness, fatigue, nausea, and plasma cell myeloma [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 76 | May 29, 2026 |
| US United States | FDA | 21 | April 24, 2026 |
| CA Canada | Health Canada | 20 | May 19, 2026 |
| EU European Union | EMA | 2 | May 29, 2026 |
GBUnited Kingdom· MHRA
76 products
Uses
g. erythroderma, pemphigus vulgaris. Autoimmune disorders/rheumatology Initial treatment of autoimmune disorders like systemic lupus erythematodes. Active phases of systemic vasculitides like panarteritis nodosa (treatment duration should be limited to two weeks in cases of concomitant positive hepatitis B serology).
g. fast proceeding destructive forms and/or extraarticular manifestations. Severe systemic course of juvenile idiopathic arthritis (Still’s disease). Haematological disorder Idiopathic thrombocytopenic purpura in adults. Oncology Palliative treatment of neoplastic diseases.
Prophylaxis and treatment of emesis induced by cytostatics, emetogenic chemotherapy within antiemetic treatment. Treatment of symptomatic multiple myeloma, acute lymphoblastic leukaemia, Hodgkin's disease and non-Hodgkin's lymphoma in combination with other medicinal products.
USUnited States· FDA
21 products
Uses
INDICATIONS AND USAGE
Allergic States Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, and serum sickness.
Dermatologic Diseases Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, and severe erythema multiforme (Stevens-Johnson syndrome). Endocrine Disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; may be used in conjunction with synthetic mineralocorticoid analogs where applicable; in infancy mineralocorticoid supplementation is of particular importance), congenital adrenal hyperplasia, hypercalcemia associated with cancer, and nonsuppurative thyroiditis.
Gastrointestinal Diseases To tide the patient over a critical period of the disease in regional enteritis and ulcerative colitis. Hematologic Disorders Acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia (Diamond-Blackfan anemia), idiopathic thrombocytopenic purpura in adults, pure red cell aplasia, and selected cases of secondary thrombocytopenia.
CACanada· Health Canada
20 products
Uses
pms-DEXAMETHASONE (dexamethasone tablets) is used orally in the management of disorders responsive to adrenocortical hormone therapy such as: • Allergic States: Control of severe or incapacitating allergic conditions not responsive to adequate trials of conventional treatment: seasonal or perennial allergic rhinitis, bronchial asthma (including status asthmaticus), laryngeal edema, contact dermatitis, atopic dermatitis, serum sickness, drug hypersensitivity reactions.
• Rheumatic Disorders: As adjunctive therapy for short term administration during an acute episode or exacerbation of psoriatic arthritis, rheumatoid arthritis including juvenile rheumatoid arthritis (selected cases may require low dose maintenance therapy), ankylosing spondylitis, acute and subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis.
• Dermatologic Diseases: Pemphigus, bullous dermatitis herpetiformis, severe erythema multiform (Stevens-Johnson syndrome), exfoliative dermatitis, mycosis fungoides, severe psoriasis, severe seborrheic dermatitis. • Ophthalmic Diseases: Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as allergic conjunctivitis, keratitis, allergic corneal marginal ulcers, herpes zoster ophthalmicus (but not herpes simplex), iritis and iridocyclitis, chorioretinitis, anterior segment inflammation, diffuse posterior uveitis and choroiditis, optic neuritis, sympathetic ophthalmia.
EUEuropean Union· EMA
2 products
Uses
1) • inflammation of the posterior segment of the eye presenting as non-infectious uveitis
How to take
Drug interactions
Known interactions involving Dexamethasone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 600. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL113110879 · revised May 15, 2026
- [2]FDA DailyMed · 12d19271-867b-41… · revised April 24, 2026 [PDF]
- [3]Health Canada (DPD) · 02279363 · revised December 12, 2025
- [4]European Medicines Agency · EMEA/H/C/001140 · revised May 29, 2026
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.