Phenylephrine
Active ingredient · 7 therapeutic classes
Sold as Omidria · COLDREX HOTREM LEMON · LEMSIP MAX ALL IN ONE · LEMSIP COLD & FLU LEMON · NIGHTTIME COLD AND FLU…
- Drug class
- Adrenergic and Dopaminergic Agents
- Availability
- Prescription and OTC
- Routes
- Oral, Intravenous, Ophthalmic, Intramuscular, Subcutaneous
- Markets covered
- 4
- Products on record
- 61
- FDA reports (12 mo)
- 15,417
Overview
Phenylephrine is an active pharmaceutical ingredient in the Adrenergic and Dopaminergic Agents group (C01CA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 46 | June 1, 2026 |
| US United States | FDA | 7 | January 26, 2026 |
| EU European Union | EMA | 1 | November 8, 2024 |
| CA Canada | Health Canada | 7 | April 22, 2026 |
GBUnited Kingdom· MHRA
46 products
Uses
Short term symptomatic relief of symptoms of influenza, feverishness, chills and colds including headache, sore throat pain, aches and pains, nasal congestion, sinusitis and its associated pain and acute nasal catarrh.
How to take
USUnited States· FDA
7 products
Uses
1 INDICATIONS & USAGE Phenylephrine hydrochloride Injection, 10 mg/mL is indicated for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia. Phenylephrine hydrochloride Injection is an alpha-1 adrenergic receptor agonist indicated for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia.
How to take
EUEuropean Union· EMA
1 product
Uses
Omidria is indicated in adults for maintenance of intraoperative mydriasis, prevention of intraoperative miosis and reduction of acute postoperative ocular pain in intraocular lens replacement surgery.
How to take
CACanada· Health Canada
7 products
7 products on record with this regulator. Detailed label text (uses, dosage, side effects) is being ingested — the original document is linked under Sources [4].
Drug interactions
Known interactions involving Phenylephrine. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL446730218 · revised March 13, 2025
- [2]FDA DailyMed · 0930ec92-5654-07… · revised November 2, 2023 [PDF]
- [3]European Medicines Agency · EMEA/H/C/003702 · revised November 8, 2024
- [4]Health Canada (DPD) · 01953583 · revised December 12, 2025
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.