Epinephrine
Active ingredient · 6 therapeutic classes
Sold as Eurneffy · Neuro II · NEFFY · EPIPEN · ANAPEN
- Drug class
- Local Hemostatics
- Availability
- Prescription and OTC
- Routes
- Intramuscular, Block/Infiltration, Nasal, Intracardiac, Subcutaneous
- Markets covered
- 4
- Products on record
- 152
- FDA reports (12 mo)
- 7,983
Overview
Epinephrine is an active pharmaceutical ingredient in the Local Hemostatics group (B02BC). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 101 | May 29, 2026 |
| CA Canada | Health Canada | 42 | May 25, 2026 |
| US United States | FDA | 8 | January 8, 2026 |
| EU European Union | EMA | 1 | June 1, 2026 |
GBUnited Kingdom· MHRA
101 products
Uses
Lidocaine 10 mg/ml (1% w/v) with Adrenaline (Epinephrine) 1:200 000 is indicated for regional anaesthesia in adults and children above 1 year of age.
How to take
CACanada· Health Canada
42 products
Uses
XYLOCAINE
Parenteral Solutions (lidocaine hydrochloride) are indicated for production of local or regional anesthesia by: • infiltration techniques including percutaneous injection, • peripheral nerve block techniques such as brachial plexus and intercostal blocks, and • central neural techniques including epidural and caudal blocks, when the accepted procedures for these techniques, as described in standard textbooks, are observed.
2 DOSAGE AND ADMINISTRATION, Recommended Dose and Dosage Adjustment). Lidocaine should be used with caution in children younger than two years of age as there are insufficient data to support the safety and efficacy of this product in this patient population at this time.
2 Geriatrics Geriatrics (> 65 years of age): Elderly patients should be given reduced doses commensurate with their age and physical condition (see 4 DOSAGE AND ADMINISTRATION, Special Populations).
USUnited States· FDA
8 products
Uses
1 INDICATIONS AND USAGE Epinephrine is a non-selective alpha and beta adrenergic agonist indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock. 1 mg/mL) is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
How to take
EUEuropean Union· EMA
1 product
Uses
EURneffy is indicated in the emergency treatment of allergic reactions (anaphylaxis) due to insect stings or bites, foods, medicinal products and other allergens as well as idiopathic or exercise induced anaphylaxis. Treatment is indicated for adults and children aged 4 years and over with a body weight of 15 kg or more.
How to take
Drug interactions
Known interactions involving Epinephrine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 363. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL144340061 · revised May 29, 2026
- [2]Health Canada (DPD) · 00001791 · revised March 22, 2025
- [3]FDA DailyMed · 0172280c-f7d6-46… · revised July 30, 2025 [PDF]
- [4]European Medicines Agency · EMEA/H/C/006139 · revised June 1, 2026
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.