Norethindrone
Active ingredient · 2 therapeutic classes
Sold as Emzahh · Vyfemla · Incassia · Aranelle · Zenchent FE
- Drug class
- Progestogens
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 3
- Products on record
- 41
- FDA reports (12 mo)
- 974
Overview
Norethindrone is an active pharmaceutical ingredient in the Progestogens group (G03AC). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 24 | May 22, 2026 |
| CA Canada | Health Canada | 9 | September 24, 2025 |
| US United States | FDA | 8 | January 31, 2026 |
GBUnited Kingdom· MHRA
24 products
Uses
Synphase is indicated for oral contraception, with the benefit of a low intake of estrogen.
How to take
CACanada· Health Canada
9 products
How to take
JENCYCLA 28-Tablet Regimen:
The dosage of JENCYCLA tablets is one tablet daily without interruption for 28 days. 28- Day Package Starting Progestin-Only Pills 1. For the initial cycle of therapy, patients should start treatment from day 1H up to and including day 5 of their menstrual period.
Then they should continue taking one tablet every day until their package is empty. Without missing a day, they should start taking JENCYCLA from a new package. H If the first progestin-only pill is taken on another day, it is recommended that an additional method of birth control (such as latex or polyurethane condoms and spermicidal foam or gel) be used every time the patient has sex during the next 48 hours.
2. If the patient has had a miscarriage or an abortion, she can start progestin-only pills the next day. 3. Patients should take one pill at the same time every day for 28 days. After finishing a pack, they should begin a new pack the next day, NOT MISSING ANY DAYS ON THE PILLS.
USUnited States· FDA
8 products
Uses
INDICATIONS AND USAGE 1. Indications Progestin - only oral contraceptives are indicated for the prevention of pregnancy. 2. 5%. However, the typical failure rate is estimated to be closer to 5%, due to late or omitted pills. The following table lists the pregnancy rates for users of all major methods of contraception.
Table 2:
Percentage of Women Experiencing an Unintended Pregnancy During the First Year of Typical Use and the First Year of Perfect Use of Contraception and the Percentage Continuing Use at the End of the First Year. United States. 1 100 Emergency Contraceptive Pills Treatment initiated within 72 hours after unprotected intercourse reduces the risk of pregnancy by at least 75%.
9 Lactational Amenorrhea Method LAM is a highly effective, temporary method of contraception. 10 Source: Trussell, J, Contraceptive Efficacy. In: Hatcher RA, Trussell J, Stewart F, Cates W, Stewart GK, Kowal D, Guest F, Contraceptive Technology: Seventeenth Revised Edition.
Drug interactions
Known interactions involving Norethindrone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 288. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL000571053 · revised December 29, 2025
- [2]Health Canada (DPD) · 02441306 · revised March 22, 2025
- [3]FDA DailyMed · 0b87cef0-610c-46… · revised September 14, 2021 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.