Levonorgestrel
Active ingredient · 2 therapeutic classes
Sold as Iclevia · Restart · Camrese · Dolishale · MIRENA
- Drug class
- Progestogens
- Availability
- Prescription and OTC
- Routes
- Oral, Intrauterine
- Markets covered
- 3
- Products on record
- 95
- FDA reports (12 mo)
- 5,695
Overview
Plain-language summary, compiled from the cited regulatory records
Levonorgestrel is a progestin [1]. It belongs to the drug class of progestogens [1]. Levonorgestrel is approved for use by females of reproductive potential to prevent pregnancy [1]. It is available in combination with ethinyl estradiol, an estrogen, for this indication [1].
This active ingredient is found in several prescription and over-the-counter products, including brands such as Iclevia, PostDay One-Step, and Restart [1]. In the past 12 months, there have been 5,695 adverse event reports associated with products containing levonorgestrel [2]. The most frequently reported adverse events in this period include device expulsion, device dislocation, genital hemorrhage, vaginal hemorrhage, and procedural pain [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 53 | May 22, 2026 |
| CA Canada | Health Canada | 29 | June 1, 2026 |
| US United States | FDA | 13 | April 3, 2026 |
GBUnited Kingdom· MHRA
53 products
Uses
Oral contraception. 4).
How to take
CACanada· Health Canada
29 products
Uses
5 mg tablet) is an emergency contraceptive that can prevent pregnancy and is intended to be used within 72 hours (three days) following known or suspected contraceptive failure or unprotected intercourse such as: • when no contraceptive has been used • when a contraceptive method may have failed, including: o condom rupture, slippage, or misuse o diaphragm or cap dislodgment, breakage, or early removal o failed coitus interruptus o miscalculation of periodic abstinence method o expelled intrauterine device o missed oral contraceptive o a delay in starting a new packet of oral contraceptives o a delay in getting a scheduled contraceptive injection • in cases of sexual assault Treatment should not be delayed as efficacy may decline with an increased interval between intercourse and the start of the treatment.
Efficacy is greatest when treatment is taken within 24 hours of unprotected intercourse, decreasing somewhat during each subsequent 24-hour period. 5 mg tablet) is calculated for a single use. If CONTINGENCY ONE is used on more than one occasion, the cumulative pregnancy rate will be higher.
USUnited States· FDA
13 products
Uses
1 INDICATIONS AND USAGE Levonorgestrel and ethinyl estradiol tablets, USP and ferrous bisglycinate tablets are indicated for use by females of reproductive potential to prevent pregnancy. Levonorgestrel and ethinyl estradiol tablets, USP and ferrous bisglycinate tablets are progestin/estrogen COC indicated for use by females of reproductive potential to prevent pregnancy.
( 1 )
How to take
Drug interactions
Known interactions involving Levonorgestrel. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 297. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL048540196 · revised May 22, 2026
- [2]Health Canada (DPD) · 02425009 · revised June 1, 2026
- [3]FDA DailyMed · 167b12a0-cdff-40… · revised December 5, 2025 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.