Nafcillin
Beta-Lactamase Resistant Penicillins
- Drug class
- Beta-Lactamase Resistant Penicillins
- Availability
- Prescription only
- Routes
- Intramuscular, Intravenous
- Markets covered
- 1
- Products on record
- 3
Overview
Plain-language summary, compiled from the cited regulatory records
Nafcillin is an antibiotic belonging to the drug class of beta-lactamase resistant penicillins [1].
This medication is approved for treating infections caused by penicillinase-producing staphylococci that are susceptible to nafcillin [1]. Before starting treatment, it is important to conduct culture and susceptibility tests to identify the specific organism causing the infection and confirm its susceptibility to nafcillin [1]. Nafcillin is not recommended for infections caused by organisms that are susceptible to penicillin G [1].
This active ingredient is available under various brand names [1].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| US United States | FDA | 3 | September 30, 2025 |
USUnited States· FDA
3 products
Uses
INDICATIONS AND USAGE
Nafcillin is indicated in the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug. Culture and susceptibility tests should be performed initially to determine the causative organism and its susceptibility to the drug (see CLINICAL PHARMACOLOGY - Susceptibility Testing ).
Nafcillin should not be used in infections caused by organisms susceptible to penicillin G. , therapy with Nafcillin for Injection should be discontinued and alternative therapy provided. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Nafcillin for Injection and other antibacterial drugs, Nafcillin for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Drug interactions
Known interactions involving Nafcillin. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]FDA DailyMed · 0556378a-b794-42… · revised February 1, 2025 [PDF]
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.