Hydrocortisone
Active ingredient · 9 therapeutic classes
Sold as Rapidol · Alkindi · Plenadren · Gerigentle · anti itch
- Drug class
- Corticosteroids Acting Locally
- Availability
- Prescription and OTC
- Routes
- Topical, Oral, Auricular (Otic), Rectal, Intravenous
- Markets covered
- 4
- Products on record
- 215
- FDA reports (12 mo)
- 7,283
Overview
Hydrocortisone is an active pharmaceutical ingredient in the Corticosteroids Acting Locally group (A07EA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 120 | May 29, 2026 |
| US United States | FDA | 76 | May 21, 2026 |
| CA Canada | Health Canada | 16 | December 23, 2025 |
| EU European Union | EMA | 3 | March 10, 2026 |
GBUnited Kingdom· MHRA
120 products
Uses
Insect bite and sting reactions
How to take
USUnited States· FDA
76 products
Uses
Uses • temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: • eczema • psoriasis • poison ivy, oak, sumac • insect bites • detergents • jewelry • cosmetics • soaps • seborrheic dermatitis • temporarily relieves external anal and genital itching • other uses of this product should only be under the advice and supervision of a doctor
How to take
CACanada· Health Canada
16 products
Uses
Hydrocortisone sodium succinate for injection USP is indicated for: 1. Endocrine Disorders • In primary, secondary and acute adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance).
• Congenital adrenal hyperplasia • Nonsuppurative thyroiditis • Hypercalcemia associated with cancer 2. Rheumatic Disorders As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: • Post-traumatic osteoarthritis • Synovitis of osteoarthritis • Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy) • Acute and subacute bursitis • Epicondylitis • Acute nonspecific tenosynovitis • Acute gouty arthritis • Psoriatic arthritis • Ankylosing spondylitis 3.
Collagen Diseases During an exacerbation or as maintenance therapy in selected cases of: • Systemic lupus erythematosus • Acute rheumatic carditis • Systemic dermatomyositis (polymyositis) 4. Dermatologic Diseases • Pemphigus • Severe erythema multiforme (Stevens-Johnson syndrome) • Exfoliative dermatitis • Bullous dermatitis herpetiformis • Severe seborrheic dermatitis • Severe psoriasis • Mycosis fungoides Hydrocortisone sodium succinate for injection USP Page 5 of 41 5.
EUEuropean Union· EMA
3 products
Uses
Replacement therapy of adrenal insufficiency in infants, children and adolescents (from birth to < 18 years old).
How to take
Drug interactions
Known interactions involving Hydrocortisone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 600. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL000140658 · revised November 8, 2024
- [2]FDA DailyMed · 00040bfe-001a-48… · revised September 17, 2024 [PDF]
- [3]Health Canada (DPD) · 02497530 · revised September 18, 2025
- [4]European Medicines Agency · EMEA/H/C/004416 · revised March 10, 2026
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.