Clonidine
Active ingredient · 3 therapeutic classes
- Drug class
- Imidazoline Receptor Agonists
- Availability
- Prescription only
- Routes
- Oral, Transdermal
- Markets covered
- 3
- Products on record
- 36
- FDA reports (12 mo)
- 2,992
Overview
Clonidine is an active pharmaceutical ingredient in the Imidazoline Receptor Agonists group (C02AC). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 19 | May 29, 2026 |
| US United States | FDA | 14 | April 20, 2026 |
| CA Canada | Health Canada | 3 | March 22, 2025 |
GBUnited Kingdom· MHRA
19 products
Uses
a) The prophylactic management of migraine or recurrent vascular headache. b) The management of vasomotor conditions commonly associated with the menopause and characterised by flushing.
How to take
USUnited States· FDA
14 products
Uses
INDICATIONS AND USAGE
Clonidine hydrochloride tablets are indicated in the treatment of hypertension. Clonidine hydrochloride tablets may be employed alone or concomitantly with other antihypertensive agents.
How to take
CACanada· Health Canada
3 products
Uses
025 mg Povidone, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium starch glycolate and tablet coating containing: FD&C Blue #2, hypromellose, polyethylene glycol, polyvinyl alcohol, talc and titanium dioxide.
INDICATIONS AND CLINICAL USE CLONIDINE (clonidine hydrochloride) is indicated for the relief of menopausal flushing in patients for whom hormonal replacement therapy is either unnecessary or not desirable.
Pediatrics (< 18 years of age):
Safety and effectiveness in children has not been established. CONTRAINDICATIONS CLONIDINE (clonidine hydrochloride) is contraindicated in patients with the following: • know hypersensitivity to the active substance or to any of the ingredients of the product.
For a complete listing, see DOSAGE FORMS, COMPOSITION AND PACKAGING section. • severe bradyarrhythmia resulting from either sick sinus syndrome or atrioventricular block of 2nd or 3rd degree; patients with sinus node function impairment.
Drug interactions
Known interactions involving Clonidine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 570. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL393070082 · revised September 12, 2025
- [2]FDA DailyMed · 00c6d67a-bb11-48… · revised May 22, 2025 [PDF]
- [3]Health Canada (DPD) · 02540061 · revised March 22, 2025
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.