Clotrimazole
Active ingredient · 3 therapeutic classes
Sold as ElixirCurozole · Rexall Jock Itch · CLOTRIMADERM TOPICAL · terrasil Antifungal… · CANESTEN COMFORTAB 3
- Drug class
- Imidazole Derivatives
- Availability
- Prescription and OTC
- Routes
- Topical, Vaginal, Oral
- Markets covered
- 3
- Products on record
- 84
- FDA reports (12 mo)
- 848
Overview
Plain-language summary, compiled from the cited regulatory records
Clotrimazole is an anti-infective and antiseptic agent used for local oral treatment [1]. It is approved to cure athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis) [1]. Clotrimazole also helps relieve the itching, irritation, redness, scaling, and discomfort associated with these fungal infections [1].
This active ingredient is available under various brand names, including ElixirCurozole, Terrasil Antifungal Cleansing Bar, and Rexall Jock Itch [1]. In the past 12 months, there have been 848 adverse event reports associated with clotrimazole [2]. The most frequently reported reactions include off-label use, drug ineffectiveness, headache, candida infection, and dyspnoea [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 35 | May 29, 2026 |
| CA Canada | Health Canada | 26 | January 20, 2026 |
| US United States | FDA | 23 | April 30, 2026 |
GBUnited Kingdom· MHRA
35 products
Uses
Canesten Thrush Internal Cream is indicated for the treatment of candidal vaginitis.
How to take
CACanada· Health Canada
26 products
Uses
CANESTEN® 6 DAY Internal Cream (clotrimazole) is indicated for the: • 6-day treatment of vaginal candidiasis. CANESTEN® 3 DAY Internal Cream (clotrimazole) is indicated for the: • 3-day treatment of vaginal candidiasis. CANESTEN® 1 DAY Internal Cream (clotrimazole) is indicated for the: • 1-day treatment of vaginal candidiasis.
CANESTEN® Combi 3 DAY (clotrimazole) is indicated for the: • 3-day treatment of vaginal candidiasis. CANESTEN® Combi 1 DAY (clotrimazole), CANESTEN® Combi 1 DAY ComforTAB® + Extra Strength External Cream (clotrimazole) and CANESTEN® Combi 1 DAY Soft Capsule + Extra Strength External Cream (clotrimazole) are indicated for the: • 1-day treatment of vaginal candidiasis.
CANESTEN® Combi 1 DAY Internal + External Creams (clotrimazole) is indicated for the: • 1-day treatment of vaginal candidiasis. CANESTEN® Extra Strength External Antifungal Cream (clotrimazole), CANESTEN® External Antifungal Cream (clotrimazole) and CANESTEN® External Cream (clotrimazole) are indicated for the: • topical treatment of external irritation causes by vulvovaginal candidiasis.
USUnited States· FDA
23 products
Uses
Uses Cures athlete’s foot (tinea pedis), jock itch (tinea cruris), ringworm (tinea corporis). Relieves the itching, irritation, redness, scaling and discomfort which can accompany these conditions.
How to take
Drug interactions
Known interactions involving Clotrimazole. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 452. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL000100654 · revised January 31, 2025
- [2]Health Canada (DPD) · 02150840 · revised March 22, 2025
- [3]FDA DailyMed · 0052992a-819c-4c… · revised February 21, 2025 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.