Amoxicillin
Penicillins With Extended Spectrum
Sold as Augmentin · NOVAMOXIN · APO-AMOXI · AURO-AMOXICLAV · MINT-AMOXI/CLAV
- Drug class
- Penicillins With Extended Spectrum
- Availability
- Prescription only
- Routes
- Oral, Intravenous
- Markets covered
- 3
- Products on record
- 266
- FDA reports (12 mo)
- 4,555
Overview
Plain-language summary, compiled from the cited regulatory records
Amoxicillin is an antibiotic belonging to the penicillin drug class with an extended spectrum [1]. It is approved for treating infections in adults and pediatric patients caused by specific bacteria [1]. These infections include lower respiratory tract infections, acute bacterial otitis media, and sinusitis [1]. The effectiveness of amoxicillin relies on the susceptibility of the bacteria to the medication, particularly in cases involving beta-lactamase-producing isolates of *Haemophilus influenzae* and *Moraxella catarrhalis* [1].
Amoxicillin is available under various brand names, including Augmentin and VOQUEZNA DUAL PAK [1]. In the past 12 months, there have been 4,555 adverse event reports associated with amoxicillin [2]. Common reasons for these reports include off-label use, diarrhea, fatigue, nausea, and the drug being ineffective [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 155 | May 22, 2026 |
| CA Canada | Health Canada | 79 | May 22, 2026 |
| US United States | FDA | 32 | February 20, 2026 |
GBUnited Kingdom· MHRA
155 products
Uses
1) such as: • Acute bacterial sinusitis • Acute otitis media • Acute streptococcal tonsillitis and pharyngitis • Acute exacerbations of chronic bronchitis • Community acquired pneumonia • Acute cystitis • Asymptomatic bacteriuria in pregnancy • Acute pyelonephritis • Typhoid and paratyphoid fever • Dental abscess with spreading cellulitis • Prosthetic joint infections • Helicobacter pylori eradication • Lyme disease Amoxicillin Powder for Oral Suspension Sugar Free is also indicated for the prophylaxis of endocarditis.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.
How to take
CACanada· Health Canada
79 products
Uses
AG-Amoxicillin (amoxicillin) may be indicated in the treatment of infections due to susceptible strains of the following micro-organisms: Gram-negative organisms: H. influenzae, P. mirabilis and N. gonorrhoeae.
Gram-positive organisms:
Streptococci (including Streptococcus faecalis and Streptococcus pneumoniae). Amoxicillin is not active against Pseudomonas aeruginosa, indole-positive Proteus species, Serratia marcescens, Klebsiella and Enterobacter species. In emergency cases, where the causative organism is not yet identified, therapy may be initiated with amoxicillin on the basis of clinical judgment while awaiting bacteriologic tests to determine its antimicrobial sensitivity.
AG-Amoxicillin may be indicated as a prophylaxis against alpha-hemolytic (Viridan's group) Streptococci before dental, oral or upper respiratory tract surgery or instrumentation. It may be also indicated as a prophylaxis of bacterial endocarditis in patients with any of the following conditions: congenital cardiac malformations, rheumatic and other acquired valvular lesions, prosthetic heart valves, previous history of bacterial endocarditis, hypertrophic cardiomyopathy, surgically constructed systemic pulmonary shunts, mitral valve prolapse with valvular regurgitation or mitral valve prolapse without valvular regurgitation but associated with thickening and/or redundancy of the valve leaflets.
USUnited States· FDA
32 products
Uses
1 INDICATIONS AND USAGE Adults and Pediatric Patients Upper Respiratory Tract Infections of the Ear, Nose, and Throat Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species.
(α- and β-hemolytic isolates only), Streptococcus pneumoniae , Staphylococcus spp. , or Haemophilus influenzae. Infections of the Genitourinary Tract Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.
Infections of the Skin and Skin Structure Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus spp. , or E. coli. Infections of the Lower Respiratory Tract Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus spp.
Drug interactions
Known interactions involving Amoxicillin. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 265. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL434610075 · revised May 22, 2026
- [2]Health Canada (DPD) · 02477726 · revised April 20, 2026
- [3]FDA DailyMed · 102c62ca-da20-48… · revised February 20, 2026 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.