POTASSIUM CHLORIDE

Posology The goal of potassium replacement therapy is to elevate the plasma concentration of the ion to within the normal range.

Dose per hour:

The maximal rate of intravenous infusion is 20mmol/hour.

Dose per day:

Since the normal dietary intake of potassium is 50 to 100mmol daily, it is rare that a larger amount is required during potassium replacement therapy. Method of administration Intravenous, after dilution. ) This solution must be diluted with not less than 50 times its volume of sodium chloride solution or other suitable diluent.

) The solution should be carefully mixed with the infusion fluid. ) The diluted injection should be administered by slow intravenous infusion at a maximal rate of 20mmol of potassium per hour. ) The ECG should be monitored continuously.

System Organ Class Frequency Adverse events Metabolism and nutrition disorders Not known Hyperkalaemia1 Nervous system disorders Not known Paraesthesia1, paralysis1 Cardiac disorders Not known Cardiac arrhythmias1, cardiac arrest1 Vascular disorders Not known Phlebitis2, hypotension1 Musculoskeletal and connective tissue disorders Not known Muscle weakness1 General disorders and administration site conditions Not known Pain2 1Excessive intake of potassium.

2Pain at the injection site and phlebitis may occur during IV administration of solutions containing 30 mmol potassium or more per litre. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.

It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine

3 • Dehydration must be corrected to ensure adequate urinary output (and potassium excretion) • Where renal excretion of potassium or cellular uptake deficient – life threatening hyperkalaemia can occur with standard doses • Extreme caution with extensive tissue destruction (eg burns) • Extreme caution in cardiac disease

3. ) Sterile Potassium Chloride Concentrate should never be used undiluted. ) Hyperkalaemia (plasma-potassium concentration above 5 mmol/litre). ) Heat cramps.