POTASSIUM CHLORIDE CONCENTRATE

Posology Adults (including elderly) and Children:

Dosage depends on the serum ionogram value and the acid-base state. 5 – actual serum potassium (MMOL)). 2). The maximal rate of infusion is 20 MMOL potassium per hour. It is recommended not to exceed 2-3 MMOL potassium per kg body weight in 24 hours.

Method of administration Potassium Chloride Concentrate 20% must be administered by slow intravenous infusion, as a dilute solution. Potassium Chloride Concentrate 20% must be diluted with not less than 70 times its volume by adding to a large volume of intravenous fluid before use.

9%, or other suitable diluent, and mixed well.

System Organ Class Frequency Adverse events Metabolism and nutrition disorders Not known Hyperkalaemia Nervous system disorders Not known Paraesthesia1, paralysis1 Cardiac disorders Not known Cardiac arrhythmias1, cardiac arrest1 Vascular disorders Not known Phlebitis Musculoskeletal and connective tissue disorders Not known Muscle weakness1 General disorders and administration site conditions Not known Extravasation2 Pain at the injection site (1)As a complication of hyperkalaemia.

(2)Adverse events noted with extravasation in the post-marketing period include oedema, erythema, pain, and blistering, which could potentially result in skin/tissue necrosis. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.

It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

Potassium Chloride Concentrate 20% must be diluted before use. 8). Plasma potassium concentration must be measured at regular intervals to avoid the development of hyperkalaemia, especially in patients with renal impairment. ECG monitoring facilities should be available.

Initial potassium replacement therapy should not involve glucose infusions, because glucose may cause a further decrease in the plasma potassium concentration. Potassium supplements should be administered with caution in patients with cardiac disease and in patients who are receiving potassium sparing diuretics or other medications which may increase plasma potassium levels.

• Hyperkalaemia • Hyperchloraemia • Impaired renal function with oliguria, anuria or azotaemia • Addison’s disease • Acute dehydration • Heat cramps