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LEM PLUS is a brand name for Phenylephrine. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: For the symptomatic relief of aches, pains, headache, sore throat, fever and nasal congestion associated with colds and influenza.
Verbatim from this product's MHRA label. Tap a section to expand.
Posology Adults, the elderly and children 16 years and over : two capsules to be taken every four to six hours, when necessary up to four times daily. Maximum dose of 8 capsules in 24 hours. Do not take the medicine for more than 3 days without consulting a doctor.
Not recommended for children under 16 years of age:
Method of administration Oral administration only.
Adverse events of paracetamol from historical clinical trial data are both infrequent and from small patient exposure. Accordingly, events reported from extensive post- marketing experience at therapeutic/labelled dose and considered attributable are tabulated below by system class.
The frequency of these adverse events is not known (cannot be estimated from available data). Paracetamol Body System Undesirable effect Blood and lymphatic system disorders Thrombocytopenia Agranulocytosis These are not necessarily causally related to paracetamol.
Immune system disorders Anaphylaxis Cutaneous hypersensitivity reactions including skin rashes, angioedema and Stevens Johnson syndrome, toxic epidermal necrolysis Respiratory, thoracic and mediastinal disorders Bronchospasm* Hepatobiliary disorders Hepatic dysfunction Skin and subcutaneous tissue disorders Very rare cases of serious skin reactions have been reported.
* There have been cases of bronchospasm with paracetamol, but these are more likely in asthmatics sensitive to aspirin or other NSAIDs. Caffeine When the recommended paracetamol-caffeine dosing regimen is combined with dietary caffeine intake, the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects such as insomnia, restlessness, anxiety, irritability, headaches, gastrointestinal disturbances and palpitations.
Adverse reactions identified through post-marketing use with caffeine are listed below. The frequency of these reactions is unknown. Body System Undesirable effect Central nervous system Dizziness Headache Phenylephrine The following adverse events have been observed in clinical trials with phenylephrine and may therefore represent the most commonly occurring adverse events.
Adverse reactions identified during post-marketing use are listed below. The frequency of these reactions are unknown. g. rash, urticaria, allergic dermatitis). Hypersensitivity reactions – including that cross-sensitivity may occur with other sympathomimetics Renal and urinary disorders Dysuria, urinary retention.
Care is advised in the administration of paracetamol to patients with renal or hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. , chronic alcoholism) who were treated with paracetamol at therapeutic dose for a prolonged period or a combination of paracetamol and flucloxacillin.
If HAGMA due to pyroglutamic acidosis is suspected, prompt discontinuation of paracetamol and close monitoring is recommended. The measurement of urinary 5-oxoproline may be useful to identify pyroglutamic acidosis as underlying cause of HAGMA in patients with multiple risk factors.
g. Raynaud's phenomenon) Cardiovascular disease This product should not be used by patients taking other sympathomimetics (such as decongestants, appetite suppressants and amphetamine-like psychostimulants) (see interactions). g. coffee, tea and some canned drinks) should be avoided while taking this product.
Keep out of sight and reach of children Do not exceed the stated dose. If symptoms persist, consult your doctor. If you are under the care of your doctor or receiving prescribed medicines consult your doctor before taking this product.
Do not take other flu, cold or decongestant medicines or other paracetamol-containing medicines with this product. Special Label Warnings Contains Paracetamol. Talk to a doctor at once if you take too much of this medicine, even if you feel well.
Do not take with any other paracetamol-containing products. Do not take with other flu, cold or decongestant products Immediate medical advice should be sought in the event of an overdose, even if you feel well. Special Leaflet Warnings Talk to a doctor at once if you take too much of this medicine, even if you feel well.
This is because too much paracetamol can cause serious liver damage.
Paracetamol: known hypersensitivity to paracetamol. Caffeine: should be given with care to patients with a history of peptic ulcer. Phenylephrine hydrochloride: should be avoided or only used with great caution in hyper-susceptible patients or those with hyperthyroidism, aneurism, hypertension, arteriosclerosis and cardiovascular disorders.
As an alpha- adrenoceptor stimulant it may provoke uterine changes which can result in foetal asphyxia.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Phenylephrine in United Kingdom.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
This is most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy. 4). Pyroglutamic acidosis may occur as a consequence of low glutathione levels in these patients.
Reporting of suspected adverse reactions:
Reporting of suspected adverse reactions after authorization of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App store.
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