DIPYRIDAMOLE

5-15ml) daily in three or four doses.

Children:

Dipyridamole is not recommended for children. Dipyridamole should usually be taken before meals.

Method of administration:

For oral use only. Shake well before use.

Adverse effects at therapeutic doses are usually mild and transient The following side effects have been reported, frequencies have been assigned based on a clinical trial (ESPS-2) in which 1654 patients received Dipyridamole alone.

4).

Reporting of suspected adverse reactions:

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard in UK.

Among other properties, dipyridamole acts as a vasodilator. g. decompensated heart failure). Patients being treated with regular oral doses of Dipyridamole should not receive additional intravenous dipyridamole. Clinical experience suggests that patients being treated with oral dipyridamole who also require pharmacological stress testing with intravenous dipyridamole, should discontinue drugs containing oral dipyridamole for twenty-four hours prior to stress testing.

5). Dipyridamole should be used with caution in patients with coagulation disorders. A small number of cases have been reported in which unconjugated dipyridamole was shown to be incorporated into gallstones to a variable extent (upto 70% by dry weight of stone).

These patients were all elderly, had evidence of ascending cholangitis and had been treated with oral dipyridamole for a number of years. There is no evidence that dipyridamole was the initiating factor in causing gallstones to form in these patients.

It is possible that bacterial deglucuronidation of conjugated dipyridamole in the bile may be the mechanism responsible for the presence of dipyridamole in gallstones. Excipients in the formulation Dipyridamole oral suspension contains liquid maltitol (E965).

Patients with a rare hereditary problem of fructose intolerance should not take this medicine. The medicine also contains methyl (E218) and propyl parahydroxybenzoates (E216) which may cause allergic reactions (possibly delayed). 20mg/5ml of propylene glycol (E1520) as an ingredient necessary for the medicine to work properly.

1. 4) the use of the product is contraindicated.