DDAVP

2mg. 1mg three times daily. This dosage regimen should then be adjusted in accordance with the patient’s response. 2mg three times daily.

Post-hypophysectomy polyuria/polydipsia:

The dose of DDAVP Tablets should be controlled by measurement of urine osmolality.

Side-effects include headache, stomach pain and nausea. Isolated cases of allergic skin reactions and more severe general allergic reactions have been reported. Very rare cases of emotional disorders including aggression in children have been reported.

Treatment with desmopressin without concomitant reduction of fluid intake may lead to water retention/hyponatraemia with accompanying symptoms of headache, nausea, vomiting, weight gain, decreased serum sodium and in serious cases, convulsions.

Care should be taken with patients who have reduced renal function and/or cardiovascular disease. In chronic renal disease the antidiuretic effect of DDAVP Tablets would be less than normal. Precautions to prevent fluid overload must be taken in: - conditions characterised by fluid and/or electrolyte imbalance - patients at risk for increased intracranial pressure

DDAVP

Tablets are contraindicated in cases of cardiac insufficiency and other conditions requiring treatment with diuretic agents. Before prescribing DDAVP Tablets the diagnoses of psychogenic polydipsia and alcohol abuse should be excluded.