Desmopressin

Desmopressin Sublingual Tablets are indicated for the treatment of vasopressin- sensitive cranial diabetes insipidus or in the treatment of post-hypophysectomy polyuria/polydipsia. Desmopressin Sublingual Tablets are also indicated for the treatment of primary nocturnal enuresis.

INDICATIONS AND USAGE

Central Diabetes Insipidus Desmopressin acetate tablets are indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region.

Desmopressin acetate is ineffective for the treatment of nephrogenic diabetes insipidus. Patients were selected for therapy based on the diagnosis by means of the water deprivation test, the hypertonic saline infusion test, and/or response to antidiuretic hormone.

Continued response to desmopressin acetate can be monitored by measuring urine volume and osmolality. Primary Nocturnal Enuresis Desmopressin acetate tablets are indicated for the management of primary nocturnal enuresis. Desmopressin acetate may be used alone or as an adjunct to behavioral conditioning or other non-pharmacologic intervention.

DESMOPRESSIN SPRAY (desmopressin acetate) is indicated for:  Management of vasopressin sensitive central diabetes insipidus.  Control of temporary polyuria and polydipsia following head trauma, hypophysectomy or surgery in the pituitary region.

1 Pediatrics Pediatrics (3 months to 12 years of age): Based on the data submitted and reviewed by Health Canada, the safety and efficacy of DESMOPRESSIN SPRAY in pediatric patients has been established. Therefore, Health Canada has authorized an indication for pediatric use.

3 Pediatrics and 7 WARNINGS AND PRECAUTIONS. 2 Geriatrics Geriatrics (> 65 years of age): Evidence from clinical experience suggests that use in the geriatric population is associated with differences in safety or effectiveness. 4 Geriatrics and 7 WARNINGS AND PRECAUTIONS.