ASCORBIC ACID

For oral administration.

Adults, the elderly and children:

For the treatment of scurvy: 2 tablets three times a day. For prophylactic use: 1 tablet twice a day.

Nervous system disorders: headache. Vascular disorders: flushing.

Gastrointestinal disorders:

Nausea, vomiting and stomach cramps. Large doses of ascorbic acid may cause diarrhoea. Skin and subcutaneous tissue disorders: redness of skin. Large doses of ascorbic acid may cause diarrhoea.

Renal and urinary disorders:

Patients known to be at risk of hyperoxaluria should not ingest ascorbic acid in doses exceeding 1 gram daily, as there may be increased urinary oxalate excretion. However such a risk has not been demonstrated in normal, non-hyperoxaluric individuals.

Ascorbic acid has been implicated in precipitating haemolytic anaemia in certain individuals with a deficiency of glucose-6-phosphate dehydrogenase. Increased intake of ascorbic acid over a prolonged period may result in an increase in renal clearance of ascorbic acid, and deficiency may result if the intake is reduced or withdrawn rapidly.

Doses of more than 600mg have a diuretic effect.

Reporting of suspected adverse reactions:

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

8). g. Labstix, Testape) and false positive results with neocuproin methods. Estimation of uric acid by phosphotungstate or by uricase with copper reduction and measurement of creatinine in non-deproteinised serum may also be affected.

High doses of vitamin C may give false negative readings in faecal occult blood tests. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicine.

Patients with rare hereditary problems of fructose or galactose intolerance, the LAPP lactase deficiency, glucose-galactose malabsorption or sucrase- isomaltase insufficiency should not take this medicine as it contains lactose and sucrose.

Hypersensitivity to ascorbic acid or any of the other ingredients. Ascorbic acid supplements should not be given to patients with hyperoxaluria.