ASCORBIC ACID

Posology Adults and children over 4 years:

Treatment: Not less than 250 mg daily in divided doses.

Maximum daily doses:

Adults and children over 12 years, 1000 mg. Children 4 – 11 years, 500 mg.

The elderly:

As for adults. As the dietary intake of vitamin C may be less in the elderly, they are at greater risk of being deficient in this vitamin. Method of administration For oral administration.

Large doses of ascorbic acid may cause diarrhoea.

Renal and urinary disorders:

Patients known to be at risk of hyperoxaluria should not ingest ascorbic acid in doses exceeding 1 gram daily, as there may be increased urinary oxalate excretion. However such a risk has not been demonstrated in normal, non-hyperoxaluric individuals.

Ascorbic acid has been implicated in precipitating haemolytic anaemia in certain individuals with a deficiency of glucose-6-phosphate dehydrogenase. Increased intake of ascorbic acid over a prolonged period may result in an increase in renal clearance of ascorbic acid, and deficiency may result if the intake is reduced or withdrawn rapidly.

Doses of more than 600mg have a diuretic effect.

Reporting of suspected adverse reactions:

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

8). g. Labstix, Tes-tape) and false positive results with neocuproin methods. Estimation of uric acid by phosphotungstate or by uricase with copper reduction and measurement of creatinine in non-deproteinised serum may also be affected.

High doses of ascorbic acid may give false negative readings in faecal occult blood tests. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency, glucose-galactose malabsorption should not take this medicine as it contains lactose.

1. Ascorbic acid should not be given to patients with hyperoxaluria.