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Trimethoprim and Methotrexate: Drug Interaction - Drugvu

🏠›Trimethoprim›Interaction with Methotrexate

Trimethoprim + Methotrexate

Drug interaction

Major interaction

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A major drug-drug interaction between Trimethoprim and Methotrexate is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “major” means

A major interaction can cause a clinically significant - sometimes serious - effect. Prescribers usually avoid this combination, or use it only with close monitoring and dose adjustments.

What to do

Do not combine these on your own. If both have been prescribed, tell your pharmacist or doctor so they can confirm it is intended and watch for problems.

The two ingredients

Active ingredient

Trimethoprim

Uses, side effects, dosage →

Active ingredient

Methotrexate

Uses, side effects, dosage →

Source

DDInter 2.0 (CC-BY 4.0, https://ddinter.scbdd.com)

This is not medical advice. Drugvu is an independent aggregator of public records.