A unknown drug-drug interaction between Methadone and Methotrexate is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “unknown” means

The severity of this interaction is not classified in the source data.

What to do

When in doubt, check with your pharmacist before combining medicines.

The two ingredients

Active ingredient

Methadone

Uses, side effects, dosage →

Active ingredient

Methotrexate

Uses, side effects, dosage →

Methadone + Methotrexate

What “unknown” means

What to do

The two ingredients

Source