Brands Browse Interactions Pill ID Categories

Loading…

Drugvu is an independent compilation of publicly-disclosed pharmaceutical regulatory information. It is not affiliated with the FDA, EMA, MHRA, Health Canada, TGA, TİTCK, PMDA, or any pharmaceutical manufacturer or regulatory agency.

This is not medical advice. Always consult a qualified healthcare professional for medical decisions.

About Editorial process Editorial team Data sources Methodology Corrections Contribute Privacy Terms DMCA Contact

Metformin and Hydrochlorothiazide: Moderate Interaction - Drugvu

🏠›Metformin›Interaction with Hydrochlorothiazide

Metformin + Hydrochlorothiazide

Drug interaction

Moderate interaction

A moderate drug-drug interaction between Metformin and Hydrochlorothiazide is recorded in public interaction data. Severity reflects the source classification; it does not describe your individual risk. Do not start, stop, or change either medicine based on this page.

What “moderate” means

A moderate interaction can matter in some people. The combination is sometimes used, but usually with caution - monitoring, timing changes, or dose adjustments.

What to do

Mention this combination to your pharmacist or prescriber. Do not stop either medicine without advice.

Side effects reported for both

Metformin and Hydrochlorothiazide are each reported to cause the effects below. Taking them together can make these more likely or more pronounced - one of the ways a drug interaction matters.

DiarrhoeaNauseaVomitingAcute Kidney InjuryFatigueHeadacheDizzinessAsthenia

Compiled from public adverse-event reports; an overlap, not a confirmed causal mechanism.

The two medicines

Active ingredient

Metformin

Biguanides

Uses, side effects, dosage →· 596 recorded interactions

Active ingredient

Hydrochlorothiazide

Thiazides, Plain

Uses, side effects, dosage →· 642 recorded interactions

Source

DDInter 2.0 (CC-BY 4.0, https://ddinter.scbdd.com)

This is not medical advice. Drugvu is an independent aggregator of public records.