Vincristine
Vinca Alkaloids and Analogues
- Drug class
- Vinca Alkaloids and Analogues
- Availability
- See label
- Routes
- Intravenous
- Markets covered
- 2
- Products on record
- 4
Overview
Vincristine is an active pharmaceutical ingredient in the Vinca Alkaloids and Analogues group (L01CA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 2 | March 6, 2026 |
| CA Canada | Health Canada | 2 | March 22, 2025 |
GBUnited Kingdom· MHRA
2 products
Uses
Vincristine sulfate is used either alone or in conjunction with other oncolytic drugs for the treatment of: 1. Leukaemias, including acute lymphocytic leukaemia, chronic lymphocytic leukaemia, acute myelogenous leukaemia and blastic crisis of chronic myelogenous leukaemia.
2. Malignant lymphomas, including Hodgkin's disease and non-Hodgkin's lymphomas. 3. Multiple myeloma. 4. Solid tumours, including breast carcinoma, small cell bronchogenic carcinoma, head and neck carcinoma and soft tissue sarcomas. 5. Paediatric solid tumours, including Ewing's sarcoma, embryonal rhabdomyosarcoma, neuroblastoma, Wilms' tumour, retinoblastoma and medulloblastoma.
6. Idiopathic thrombocytopenic purpura. Patients with true ITP refractory to splenectomy and short-term treatment with adrenocortical steroids may respond to vincristine sulfate but the medicinal product is not recommended as primary treatment of this disorder.
Recommended weekly doses of vincristine sulfate given for 3 to 4 weeks have produced permanent remissions in some patients. If patients fail to respond after 3 to 6 doses, it is unlikely that there will be any beneficial results with additional doses.
CACanada· Health Canada
2 products
2 products on record with this regulator. Detailed label text (uses, dosage, side effects) is being ingested — the original document is linked under Sources [2].
Drug interactions
Known interactions involving Vincristine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 455. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL045150008 · revised March 6, 2026
- [2]Health Canada (DPD) · 02143305 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.