ℹ️ Compiled from public regulatory records · Last regulator revision: May 27, 2026🚩 Report this page

Tranylcypromine

Monoamine Oxidase Inhibitors, Non-Selective

Sold as PARNATE

GB MHRACA Health Canada

Drug class: Monoamine Oxidase Inhibitors, Non-Selective
Availability: See label
Routes: Oral
Markets covered: 2
Products on record: 24

N06AFMonoamine Oxidase Inhibitors, Non-Selective

Overview

Tranylcypromine is an active pharmaceutical ingredient in the Monoamine Oxidase Inhibitors, Non-Selective group (N06AF). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.

Regulatory status by market

Market	Regulator	Products	Last revision
GB United Kingdom	MHRA	22	May 27, 2026
CA Canada	Health Canada	2	March 22, 2025

GBUnited Kingdom· MHRA

22 products

Uses

GBOfficial regulatory label· revised January 9, 2026[1]

Tranylcypromine is indicated for the treatment of Major Depressive Episodes in adult patients when treatment with other types of antidepressant medication has failed.

How to take

CACanada· Health Canada

2 products

Uses

CAOfficial regulatory label· revised March 22, 2025[2]

PARNATE (tranylcypromine sulfate) is indicated for the treatment of major depressive disorder (MDD) in adult patients who have not responded adequately to other antidepressants. PARNATE is not indicated for the initial treatment of MDD due to the potential for serious adverse reactions and drug interactions, and the need for dietary restrictions.
Pediatrics Pediatrics (<18 years of age):
PARNATE is not indicated for use in children or adolescents less than 18 years of age.
Geriatrics Geriatrics:
No data are available.

How to take

Drug interactions

Known interactions involving Tranylcypromine. Select one for details. This list is informational and not a complete interaction checker.

Alfentanil Almotriptan Amitriptyline Amoxapine Amphetamine Apraclonidine Atomoxetine Benzhydrocodone Benzphetamine Buprenorphine Bupropion Buspirone Butorphanol Carbamazepine Citalopram Clomipramine Cocaine Codeine Cyclobenzaprine Desflurane Desipramine Desvenlafaxine Deutetrabenazine Dexfenfluramine Dexmethylphenidate Dextroamphetamine Dextromethorphan Dezocine Diethylpropion Dihydrocodeine Dihydroergotamine Dolasetron Dopamine Doxapram Doxepin Doxylamine Droperidol Duloxetine Eletriptan Enflurane Entacapone Ephedrine Ergotamine Escitalopram Esketamine Etomidate Fenfluramine Fentanyl Fluoxetine Fluvoxamine Fospropofol Frovatriptan Granisetron Halothane Hydrocodone Hydromorphone Imipramine Iohexol Iopamidol Isocarboxazid Isoflurane Isometheptene Ketamine Lasmiditan Levodopa Levomilnacipran Levorphanol Linezolid Lisdexamfetamine Lorcaserin Maprotiline Mazindol Meperidine Mephentermine Metaraminol Methadone Methohexital Methoxyflurane Methyldopa Methylene Blue Methylphenidate Milnacipran Mirtazapine Morphine Nalbuphine Naratriptan Nefazodone Nitrous Oxide Nortriptyline Oliceridine Ondansetron Opicapone Opium Oxcarbazepine Oxycodone Oxymorphone Ozanimod Palonosetron Paroxetine Pentazocine Phendimetrazine Phenelzine Phentermine Phenylephrine Phenylpropanolamine Procarbazine Propofol Propoxyphene Protriptyline Pseudoephedrine Rasagiline Remifentanil Rizatriptan Safinamide Selegiline Sertraline Sevoflurane Sibutramine Solriamfetol Sufentanil Sumatriptan Tapentadol Tetrabenazine Thiopental Tolcapone Tramadol Trazodone Trimipramine Tryptophan Valbenazine Venlafaxine Vilazodone Vortioxetine Zolmitriptan Acebutolol Acetohexamide Acrivastine Albuterol Aldesleukin Alfuzosin Aliskiren Alprazolam Altretamine Amifampridine Amiloride Amlodipine Amobarbital Amyl Nitrite Apomorphine Arformoterol Aripiprazole Asenapine Atenolol Avanafil Azatadine Azelastine Azilsartan Baclofen Benazepril Bendroflumethiazide Benzthiazide Bepridil Betaxolol Bisoprolol Brexanolone Brexpiprazole Brimonidine Brivaracetam Bromocriptine Brompheniramine Bumetanide Butabarbital Butalbital Cannabidiol Captopril Carbinoxamine Cariprazine Carisoprodol Carteolol Carvedilol Cenobamate Cetirizine Chlorcyclizine Chlordiazepoxide Chlormezanone Chlorothiazide Chlorphenesin Chlorpheniramine Chlorpromazine Chlorpropamide Chlorthalidone Chlorzoxazone Clemastine Clevidipine Clobazam Clonazepam Clonidine Clorazepate Clozapine Cyclandelate Cyclizine Cyproheptadine Dantrolene Deserpidine Dexbrompheniramine Dexmedetomidine Diazepam Diazoxide Diltiazem Diphenhydramine Dipivefrin Disulfiram Dobutamine Doxazosin Dronabinol Droxidopa Enalapril Epinephrine Eplerenone Epoprostenol Eprosartan Eslicarbazepine Esmolol Estazolam Eszopiclone Ethacrynate Ethanol Ethosuximide Ethotoin Ezogabine Felbamate Felodipine Fenoldopam Flavoxate Flibanserin Fluphenazine Flurazepam Formoterol Fosinopril Fosphenytoin

Showing 240 of 459. Type above to find a specific drug.

Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.

Sources & citations

[1]MHRA (UK) · PL204160968 · revised January 9, 2026
[2]Health Canada (DPD) · 01919598 · revised March 22, 2025

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.