Trabectedin
Other Plant Alkaloids and Natural Products
Sold as Yondelis
- Drug class
- Other Plant Alkaloids and Natural Products
- Availability
- See label
- Routes
- Intravenous
- Markets covered
- 3
- Products on record
- 12
Overview
Trabectedin is an active pharmaceutical ingredient in the Other Plant Alkaloids and Natural Products group (L01CX). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 8 | May 1, 2026 |
| EU European Union | EMA | 2 | March 25, 2026 |
| CA Canada | Health Canada | 2 | November 19, 2025 |
GBUnited Kingdom· MHRA
8 products
Uses
Trabectedin is indicated for the treatment of adult patients with advanced soft tissue sarcoma, after failure of anthracyclines and ifosfamide, or who are unsuited to receive these agents. Efficacy data are based mainly on liposarcoma and leiomyosarcoma patients.
Trabectedin in combination with pegylated liposomal doxorubicin (PLD) is indicated for the treatment of patients with relapsed platinum-sensitive ovarian cancer.
How to take
EUEuropean Union· EMA
2 products
Uses
Trabectedin Accord is indicated for the treatment of adult patients with advanced soft tissue sarcoma, after failure of anthracyclines and ifosfamide, or who are unsuited to receive these agents. Efficacy data are based mainly on liposarcoma and leiomyosarcoma patients.
Trabectedin Accord in combination with pegylated liposomal doxorubicin (PLD) is indicated for the treatment of patients with relapsed platinum-sensitive ovarian cancer.
How to take
CACanada· Health Canada
2 products
Uses
AND CLINICAL USE .................................................................................. 3 CONTRAINDICATIONS ........................................................................................................ 4 WARNINGS AND PRECAUTIONS ......................................................................................
4 ADVERSE REACTIONS....................................................................................................... 11 DRUG INTERACTIONS .......................................................................................................
19 DOSAGE AND ADMINISTRATION................................................................................... 21 OVERDOSAGE ......................................................................................................................
25 ACTION AND CLINICAL PHARMACOLOGY ............................................................... 25 STORAGE AND STABILITY............................................................................................... 27 SPECIAL HANDLING INSTRUCTIONS ...........................................................................
Drug interactions
Known interactions involving Trabectedin. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 397. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL068310332 · revised February 27, 2026
- [2]European Medicines Agency · EMEA/H/C/006433 · revised March 25, 2026
- [3]Health Canada (DPD) · 02351528 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.