Sulfasalazine

Induction and maintenance of remission of ulcerative colitis and treatment of active Crohn's disease.

C. should be adjusted according to the response to the treatment and the patient's tolerance to the drug. The tablets / delayed-release tablets should be taken at regular and even intervals over the 24-hour period. C. tablets should preferably be taken with a meal.

For intestinal inflammatory diseases, the night-time doses interval should not exceed 8 hours. Patients not previously treated with sulfasalazine should increase the dose gradually during the first few weeks. The incidence of adverse reactions tends to increase with daily dosages of 4 g or more; patients receiving these doses should be advised of this possibility and should be carefully observed for the appearance of adverse reactions.

Recommended Dose and Dosage Adjustment Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease 1.

Acute attacks:

Adults: Severe attacks: 2–4 tablets, 3–4 times daily Moderate and mild attacks: 2 tablets, 3–4 times daily. Children: 25–35 kg body weight: 1 tablet, 3 times daily 35–50 kg body weight: 2 tablets, 2-3 times daily 2.

INDICATIONS AND USAGE

Sulfasalazine Tablets are indicated: a) in the treatment of mild to moderate ulcerative colitis, and as adjunctive therapy in severe ulcerative colitis; and b) for the prolongation of the remission period between acute attacks of ulcerative colitis.