Sodium Polystyrene Sulfonate

SOLYSTAT (sodium polystyrene sulfonate) is for oral or rectal administration only. The dosage recommendations given below are approximate. The precise requirements for each individual patient should be determined on the basis of regular clinical and biochemical assessments.

Powder for Suspension Suspensions of SOLYSTAT should be freshly prepared and not stored beyond 24 hours. SOLYSTAT powder should not be heated as heating may alter the exchange properties of the resin.

Adults, Including the Elderly Oral:

The average daily adult dose of SOLYSTAT is 15 to 60 grams. This is provided by administering 15 grams (approximately 4 level teaspoons) of SOLYSTAT one to four times daily. 5 grams of SOLYSTAT powder and 15 mmol of sodium. A heaping teaspoon may contain as much as 10-12 grams of SOLYSTAT powder.

Since the in vivo efficiency of sodium-potassium exchange resins is approximately 33 per cent, about one third of the resin’s actual sodium content is being delivered to the body. Each dose should be given as a suspension in a small quantity of water or, for greater palatability, in syrup, but not in orange juice or other fruit juices that are known to contain potassium.

1 INDICATIONS AND USAGE Sodium polystyrene sulfonate for suspension is indicated for the treatment of hyperkalemia. 2) ] Sodium polystyrene sulfonate for suspension is a potassium binder indicated for the treatment of hyperkalemia ( 1 ).

Limitation of Use :

Sodium polystyrene sulfonate for suspension should not be used an emergency treatment for life threatening hyperkalemia because of its delayed onset of action ( 1 ).

Resonium A is an ion-exchange resin that is recommended for the treatment of hyperkalaemia associated with anuria or severe oliguria. It is also used to treat hyperkalaemia in patients requiring dialysis and in patients on regular haemodialysis or on prolonged peritoneal dialysis.