Sodium Hydroxide: Uses, Side Effects, Dosage - Drugvu

ℹ️ Compiled from public regulatory records · Last regulator revision: May 1, 2026

Sodium Hydroxide

Active ingredient

GB MHRA

Drug class: -
Availability: See label
Markets covered: 1
Products on record: 2

Overview

Sodium Hydroxide is an active pharmaceutical ingredient. The information below is compiled per regulator from the product labels on record, with direct links to the original documents.

Regulatory status by market

Market	Regulator	Products	Last revision
GB United Kingdom	MHRA	2	May 1, 2026

GBUnited Kingdom· MHRA

2 products

Uses

GBOfficial regulatory label· revised May 1, 2026[1]

Hartmann’s solution is indicated for the treatment of metabolic acidosis and dehydration with acidosis. It may be used to expand extracellular fluids or restore extracellular electrolyte. It may be used in the treatment of diabetic coma.
For intravenous infusion.

How to take

Sources & citations

[1]MHRA (UK) · PL088280045 · revised May 1, 2026

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.

Side effects & warnings

GBOfficial regulatory label· Adverse reactions· revised May 1, 2026[1]

Thrombosis of the chosen vein is always possible with intravenous infusion. 2. 5). Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product.
uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

GBOfficial regulatory label· Warnings and precautions· revised May 1, 2026[1]

Although Hartmann's solution provides potassium, this is only enough to maintain the potassium content of extracellular fluid and would be quite inadequate for patients with severe potassium loss. Under these circumstances potassium supplements must be given.
Lactate overdose in, patients with heart disease may provoke arrhythmias and heart failure. ECG monitoring is recommended if Hartmann's solution is administered to such patients use with caution in, patients with cardiac failure, hypertension, impaired renal function, peripheral and pulmonary oedema and in toxaemia of pregnancy.
The label states:
Do not use unless the solution is clear and free from particles. High volume infusion must be used under specific monitoring in patients with cardiac or pulmonary failure, and in patients with non-osmotic vasopressin release (including SIADH), due to the risk of hospital-acquired hyponatraemia (see below).
g. 5) are at particular risk of acute hyponatraemia upon infusion of hypotonic fluids. Acute hyponatraemia can lead to acute hyponatraemic encephalopathy (cerebral oedema) characterized by headache, nausea, seizures, lethargy and vomiting.
Patients with cerebral oedema are at particular risk of severe, irreversible and life-threatening brain injury. g. meningitis, intracranial bleeding, cerebral contusion and brain oedema) are at particular risk of the severe and life-threatening brain swelling caused by acute hyponatraemia.

This is not medical advice. Consult a qualified healthcare professional.