Sevoflurane
Halogenated Hydrocarbons
Sold as SEVORANE AF
- Drug class
- Halogenated Hydrocarbons
- Availability
- Prescription only
- Routes
- Inhalation, Respiratory (Inhalation)
- Markets covered
- 3
- Products on record
- 9
- FDA reports (12 mo)
- 593
Overview
Plain-language summary, compiled from the cited regulatory records
Sevoflurane is a halogenated hydrocarbon used for general anesthesia [1]. It is indicated for both the induction and maintenance of general anesthesia in adult and pediatric patients undergoing inpatient and outpatient surgical procedures [1]. Administration of sevoflurane should only be performed by individuals trained in the administration of general anesthesia [1].
Facilities for maintaining a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be readily available when using sevoflurane [1]. Because the level of anesthesia can change rapidly, only specific types of vaporizers should be used [1].
In the past 12 months, there have been 593 adverse event reports associated with sevoflurane [2]. Common adverse events reported include acute kidney injury, drug interaction, hypotension, neurological complications from anesthesia, and malignant hyperthermia [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 4 | May 27, 2026 |
| GB United Kingdom | MHRA | 3 | May 22, 2026 |
| US United States | FDA | 2 | March 23, 2026 |
CACanada· Health Canada
4 products
Uses
SEVORANE AF (sevoflurane) is indicated for: induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery. 3 Pediatrics. 4 Geriatrics.
How to take
GBUnited Kingdom· MHRA
3 products
Uses
Sevoflurane is indicated for induction and maintenance of general anaesthesia in adult and paediatric patients for inpatient and outpatient surgery.
How to take
USUnited States· FDA
2 products
Uses
INDICATIONS AND USAGE
Sevoflurane, USP is indicated for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery. Sevoflurane, USP should be administered only by persons trained in the administration of general anesthesia.
Facilities for maintenance of a patent airway, artificial ventilation, oxygen enrichment, and circulatory resuscitation must be immediately available. Since level of anesthesia may be altered rapidly, only vaporizers producing predictable concentrations of sevoflurane, USP should be used.
How to take
Drug interactions
Known interactions involving Sevoflurane. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 354. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 02172763 · revised May 27, 2026
- [2]MHRA (UK) · PL410420004 · revised September 6, 2024
- [3]FDA DailyMed · 06b9f724-6425-49… · revised November 6, 2025 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.