Propafenone
Antiarrhythmics, Class Ic
- Drug class
- Antiarrhythmics, Class Ic
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 2
- Products on record
- 6
Overview
Propafenone is an active pharmaceutical ingredient in the Antiarrhythmics, Class Ic group (C01BC). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 4 | May 1, 2026 |
| US United States | FDA | 2 | March 23, 2024 |
GBUnited Kingdom· MHRA
4 products
Uses
Propafenone is indicated for the prophylaxis and treatment of ventricular arrhythmias. Propafenone is also indicated for the prophylaxis and treatment of paroxysmal supraventricular tachyarrhythmias which include paroxysmal atrial flutter/fibrillation and paroxysmal re-entrant tachycardia’s involving the AV node or accessory bypass tracts, when standard therapy has failed or is contraindicated.
How to take
USUnited States· FDA
2 products
Uses
1 INDICATIONS AND USAGE Propafenone hydrochloride tablets are indicated to: prolong the time to recurrence of paroxysmal atrial fibrillation/flutter (PAF) associated with disabling symptoms in patients without structural heart disease.
prolong the time to recurrence of paroxysmal supraventricular tachycardia (PSVT) associated with disabling symptoms in patients without structural heart disease. treat documented ventricular arrhythmias, such as sustained ventricular tachycardia that, in the judgment of the physician, are life-threatening.
Initiate treatment in the hospital.
Usage Considerations:
The use of propafenone hydrochloride tablets in patients with permanent atrial fibrillation (AF) or in patients exclusively with atrial flutter or PSVT has not been evaluated. Do not use propafenone hydrochloride tablets to control ventricular rate during AF.
Drug interactions
Known interactions involving Propafenone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 391. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL200750356 · revised May 1, 2026
- [2]FDA DailyMed · 0c887381-42fe-4f… · revised July 21, 2023 [PDF]
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.