Posology Adults Two bottles of Izinova are needed for appropriate cleansing of the bowel. 5 litres, and must be followed by the ingestion of an additional 1 litre of water or clear liquid within 2 hours. Authorised clear liquids are: water, tea or coffee (no milk or non-dairy creamer), fizzy (carbonated) or still (non-carbonated) soft drinks, strained fruit juices without pulp (not coloured red or purple), clear soup or soup strained to remove any solids.
In total, the volume of liquid intake required for bowel cleansing is approximately 3 litres taken orally prior to the procedure. This medicine can be taken either as a split-dose (two-day; with the first bottle taken the night before the procedure, and the second to be taken the following morning), or as a one-day oral preparation as described below (see Method of administration).
The exact regimen and rate of ingestion of Izinova may be determined by the physician. If allowed by the timing of the procedure, the split-dose regimen should be favoured over the one-day regimen. The one-day dose regimen is a potentially useful alternative regimen.
5 litres). : approximately 1 litre) over the next two hours. 5 litres). : approximately 1 litre) over the next two hours. The intake of the whole diluted solution of Izinova and additional liquid (water or clear liquid) should be completed: - In the absence of anaesthesia, at least one hour prior to the start of the procedure.
- In case of anaesthesia, usually at least 2 hours prior to the start of the procedure, in accordance with the instructions of the anaesthetist. 5 litres). : approximately 1 litre) over the next two hours. 5 litres). : approximately 1 litre) over the next two hours.
The intake of the whole diluted solution of Izinova and additional liquid (water or clear liquid) should be completed: - In the absence of anaesthesia, at least one hour prior to the start of the procedure. - In case of anaesthesia, usually at least 2 hours prior to the start of the procedure, in accordance with the instructions of the anaesthetist.
After the procedure In order to replace fluid lost during the preparation for the procedure, patients should be encouraged to drink a sufficient amount of fluids afterwards to maintain adequate hydration. Dietary restrictions The day prior to the procedure, a light breakfast may be consumed.
Afterwards the patient should only have clear liquids for lunch, dinner and any other meals until the procedure is performed. Red and purple liquids, milk and alcoholic beverages should be avoided. 1]. 4]. Patients with renal impairment Insufficient data are available for this population.
Dose adjustment is not required in the patients with mild to moderate renal impairment however special precautions should be taken in this population as for any high-risk population. 4). Patients with hepatic impairment Insufficient data are available for this population.
4). e. patients below 18 years old) have not yet been established. 1).