Pimozide
Diphenylbutylpiperidine Derivatives
Sold as ORAP
- Drug class
- Diphenylbutylpiperidine Derivatives
- Availability
- See label
- Routes
- Oral
- Markets covered
- 2
- Products on record
- 6
Overview
Pimozide is an active pharmaceutical ingredient in the Diphenylbutylpiperidine Derivatives group (N05AG). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 3 | August 8, 2025 |
| CA Canada | Health Canada | 3 | March 22, 2025 |
GBUnited Kingdom· MHRA
3 products
Uses
Orap is an antipsychotic of the diphenylbutyl-piperidine series and is indicated in: - Chronic schizophrenia, for the treatment of symptoms and prevention of relapse. - Other psychoses, especially paranoid and monosymptomatic hypochondriacal psychoses (eg delusional parasitosis).
Orap is indicated in adults and children over 12 years old.
How to take
CACanada· Health Canada
3 products
How to take
A single morning dose is recommended for all patients. Adults The initial recommended dose in patients with chronic schizophrenia for whom pimozide might be indicated is 2 to 4 mg once daily, with weekly increments of 2 to 4 mg until a satisfactory level of therapeutic effect is attained or excessive adverse effects occur.
The average maintenance dose is 6 mg daily with the usual range of 2 to 12 mg per day. Daily doses above 20 mg are not recommended. The patients should be reviewed regularly to ensure the minimum effective dose is being used. Elderly patients The maintenance dose is the same as in adults but it is recommended to start with half of the adult starting dose.
56 Melting Range: 214-218oC.
Description:
White to creamy-white crystalline powder. 18 Composition: pms-PIMOZIDE, 2 mg Tablets contain 2 mg Pimozide USP and following non-medicinal ingredients: Calcium Stearate, Lactose, Microcrystalling Cellulose, Starch (Corn). pms-PIMOZIDE, 4 mg Tablets contain 4 mg Pimozide USP and following non-medicinal ingredients: Calcium Stearate, Lactose, Microcrystalling Cellulose, Starch (Corn), FD&C Blue #1 Lake 13% and FD&C Yellow #5 Lake 15%.
Drug interactions
Known interactions involving Pimozide. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 542. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL217720004 · revised July 4, 2025
- [2]Health Canada (DPD) · 02239831 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.